WHO Classification of Tumours of the Central Nervous System

Author: International Agency for Research on Cancer,Otmar D. Wiestler

Publisher: International Agency for Research on Cancer

ISBN: 9789283244929

Category: Medical

Page: 408

View: 8746

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WHO Classification of Tumours of the Central Nervous System is the revised fourth edition of the WHO series on histological and genetic typing of human tumors. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. The book, prepared by 122 authors from 19 countries, contains more than 800 color images and tables, and more than 2800 references.

Diagnostic Histopathology of Tumors

Author: Christopher D. M. Fletcher

Publisher: Elsevier Health Sciences

ISBN: 1455737542

Category: Medical

Page: 2296

View: 2961

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Diagnose tumors with confidence with Diagnostic Histopathology of Tumors, 4th Edition. Dr. Christopher Fletcher's renowned reference provides the advanced, expert guidance you need to evaluate and interpret even the most challenging histopathology specimens more quickly and accurately. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Diagnose efficiently and effectively using diagnostic flow charts, correlations of gross appearances to microscopic findings, and differential diagnosis tables for better recognition and evaluation of similar-looking entities. Employ immunohistochemistry, molecular and genetic diagnostic tests, and other modern techniques as well as the best morphologic diagnostic methods to effectively identify each tumor or tumor-like entity. Utilize new, clinically important molecular genetic data and updated classification schemes to help guide treatment and targeted therapy. Apply the latest techniques and diagnostic criteria with completely rewritten chapters on Small and Large Intestines, Heart, Larynx and Trachea, Ear, and Peritoneum. Find critical information quickly thanks to more tables and bulleted lists throughout.

Brain Tumors E-Book

An Encyclopedic Approach

Author: Andrew H. Kaye,Edward R. Laws Jr

Publisher: Elsevier Health Sciences

ISBN: 0702048186

Category: Medical

Page: 1088

View: 1118

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Meet the increasing need for effective brain tumor management with the highly anticipated revision of Brain Tumors by Drs. Andrew H. Kaye and Edward R. Laws. Over the past decade, enormous advances have been made in both the diagnosis and the surgical and radiotherapeutic management of brain tumors. This new edition guides you through the latest developments in the field, including hot topics like malignant gliomas, functional brain mapping, neurogenetics and the molecular biology of brain tumors, and biologic and gene therapy. Benefit from the knowledge and experience of Drs. Andrew H. Kaye and Edward R. Laws, globally recognized experts in the field of neurosurgery, as well as many other world authorities.

Modern Surgical Pathology E-Book

Author: Noel Weidner,Richard J. Cote,Saul Suster,Lawrence M. Weiss

Publisher: Elsevier Health Sciences

ISBN: 1437719589

Category: Medical

Page: 2432

View: 5332

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Modern Surgical Pathology, 2nd Edition presents today's most complete, current, and practical assistance in evaluating and signing out surgical specimens. Nearly 3,000 high-quality color pathology images provide a crystal-clear basis for comparison to any sample you see under the microscope. Clinical, gross, microscopic, immunohistochemical, and molecular genetic features are integrated as appropriate for all tumors and tumor-like lesions, addressing all of the investigative contexts relevant to formulating an accurate diagnosis. Edited by four leading surgical pathologists - Noel Weidner, MD, Richard J. Cote, MD, Saul Suster, MD and Lawrence M. Weiss, MD - with contributions from more than 70 other experts, Modern Surgical Pathology, 2nd Edition delivers the well-rounded, well-organized, richly illustrated, user-friendly guidance you need to efficiently arrive at confident diagnoses for even the most challenging lesions. Contributions from many leading surgical pathologists give you well-rounded, expert answers to any question that you may face. Clinical, gross, microscopic, immunohistochemical, and molecular genetic features are correlated as appropriate for every type of surgical pathology specimen, addressing all of the investigative contexts relevant to formulating an accurate diagnosis and thereby ensuring a completely accurate surgical report. Nearly 3,000 brand-new, high-quality color pathology images provide a crystal-clear basis for comparison to any specimen you see under the microscope. A completely rewritten section on the female reproductive tract offers many more illustrations of common entities to help you more easily distinguish between tumors and tumor-like lesions. Expanded coverage of non-neoplastic diseases and disorders makes it easier to recognize benign conditions that can mimic malignancy. The latest classification schemes and criteria for malignancy, incorporated throughout, enable you to include the most current gradings in your reports. A new, more consistent organization explores anatomy/histology, gross and microscopic appearance, adjunct techniques, diagnosis, and differential diagnosis for each neoplastic or non-neoplastic lesion, facilitating rapid consultation in the reporting room. An increased number of differential diagnosis and classification tables expedite diagnosis.

Central Nervous System Malignancies, An Issue of Hematology/Oncology Clinics of North America - E-Book

Author: Jill Lacy,Joachim M. Baehring

Publisher: Elsevier Health Sciences

ISBN: 1455747637

Category: Medical

Page: 240

View: 1244

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Topics include: Neoplastic Meningitis and Epidural Metastases: Evaluation and Management; Management of Brain Metastases: Surgery, Radiation, or Both?; Meningiomas/Nerve Sheath Tumors/Pituitary Tumors: Diagnosis and Treatment; Medulloblastoma/Primitive Neuroectodermal Tumor and Germ Cell Tumors: The Uncommon but Potentially Curable Primary Brain Tumors; Primary CNS Lymphoma: Overview of Current Treatment Strategies; Anaplastic Gliomas: Radiation, Chemotherapy, or Both?; Low Grade Gliomas: When and How to Treat?; Glioblastoma Multiforme: Overview of Current Treatment and Future Perspectives.

Brain Tumors

Author: Mark Cohen, MD,David E. Elder, MB, ChB,Bette K. Kleinschmidt-DeMasters, MD,Richard Prayson, MD

Publisher: Demos Medical Publishing

ISBN: 9781935281368

Category: Medical

Page: 224

View: 5474

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Surgical neuropathology is a challenging arena for many pathologists, due in large part to a relative lack of experience of most pathologists in this area compared to other areas of surgical pathology. Brain Tumors is intended to address this need with cases drawn from the surgical neuropathology practices of the authors. This volume provides examples of over 100 brain tumors, running the gamut from the very common to the rare. Each example is presented in a case based format and the wide variety of cases presented covers the entire scope of brain tumors and offers the opportunity to review both the basics for the beginner or relatively inexperienced pathologist and also offers experienced pathologists the chance to see some of the rare entities. Each case is formatted as if it were a consult case and includes a brief clinical history, description of the pathologic findings with numerous illustrations, the line diagnosis, discussion of the entity, and the diagnostic thought process as well pertinent references for further reading. When relevant, current practical applications of immunohistochemistry and molecular pathology are discussed. The Consultant Pathology Series The Consultant Pathology series is designed to disseminate the knowledge of expert surgical pathology consultants in the analysis and diagnosis of difficult cases to the full community of pathology practitioners. The volumes are based on actual consultations and presented in a format that illustrates the expert's process of evaluating the case, including indications for consultation, the consultants findings and comment, and discussion of the entity that amplifies the case description. Each volume in the Consultant Pathology series is authored by international experts with extensive case experience in the areas covered

Brain Tumors

Their Biology and Pathology

Author: Klaus Joachim Zülch

Publisher: Springer-Verlag

ISBN: 1489965718

Category: Medical

Page: 308

View: 6304

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Clinical Neurology E-Book

A Primer

Author: Peter Gates

Publisher: Elsevier Health Sciences

ISBN: 0729579352

Category: Medical

Page: 450

View: 7017

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Please note that this eBook does not include the DVD accompaniment. If you would like to have access to the DVD content, please purchase the print copy of this title. This is a clinical neurology book for students and non neurologists, and for those who teach them. The book covers neuroanatomy, history taking and examination and then proceeds to discuss the clinical features of common problems as well as selected, less common neurological disorders, in a way that will demystify a part of medicine that many find complex and difficult to understand. The book is accompanied by a DVD explaining concepts, demonstrating techniques of performing the neurological examination and demonstration of abnormal neurological signs. The first chapter is devoted to neuroanatomy from a clinical viewpoint. The concept of localising problems by likening the nervous system to a map grid with vertical meridians of longitude (the ascending sensory pathways and the descending motor pathway)and horizontal parallels of latitude (cortical signs, brainstem cranial nerves, nerve roots and peripheral nerves) of the nervous system is developed. Subsequent chapters take the reader through the neurological examination and the common neurological presentations from a symptom oriented approach. Chapter 4 contains a very simple method of understanding the brainstem, the "rule of 4". Chapter 6 discusses the approach after the history and examination are completed. The final chapter is an overview of how to approach information gathering and keeping up-to-date using the complex information streams available. widely illustrated with case studies and illustrations key points clinical questions clinical orientation with comprehensive references

Rosai and Ackerman's Surgical Pathology E-Book

Author: Juan Rosai

Publisher: Elsevier Health Sciences

ISBN: 032308804X

Category: Medical

Page: 2892

View: 2987

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Rosai and Ackerman’s Surgical Pathology delivers the authoritative guidance you need to overcome virtually any challenge in surgical pathology. Recognized globally for his unmatched expertise, preeminent specialist Juan Rosai, MD brings you state-of-the-art coverage of the latest advancements in immunohistochemistry, genetics, molecular biology, prognostic/predictive markers, and much more - equipping you to effectively and efficiently diagnose the complete range of neoplastic and non-neoplastic entities. Efficiently review the clinical presentation, gross and microscopic features, ultrastructural and immunohistochemical findings, differential diagnosis, therapy, and prognosis for virtually every pathologic entity. Compare your findings to more than 3,300 outstanding illustrations that capture the characteristic presentation of every type of lesion. Avoid diagnostic pitfalls using Dr. Rosai's expert observations on what to look for, what to be careful about, and which presentations can be misleading. Find quick answers on tumor staging, quality control procedures, and the handling of gross specimens through valuable appendices. Make optimal use of all the very latest advances including our increased understanding of the genetic basis of inherited and acquired disease, the newest molecular genetic and immunohistochemical techniques, and the most recent WHO disease classification schemes.

Neuroradiology Applications of High-Field MR Imaging, An Issue of Neuroimaging Clinics - E-Book

Author: Winfried A. Willinek

Publisher: Elsevier Health Sciences

ISBN: 1455744166

Category: Medical

Page: 297

View: 2173

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Information for neuroimaging specialists includes a "Diagnostic Checklist or “Clinical Recommendations along with tables presenting recommended MR sequences and protocols. The primary focus of the issue is 3.0T; one article specifically deals with 7T and higher fields are mentioned sporadically throughout. Topics include: Tumor High-Field MR; Stroke High-Field MR; High-Field MR of Inflammation; Vascular Disorders: MR Angiography of Brain Vessels, MR Angiography of Neck Vessels, and Perfusion Imaging; Plaque Imaging; Neurodegenerative Disease; Epilepsy Imaging; Head and Neck Oncology Applications; Pediatric High-Field Imaging; Spine High-Field Imaging; Ultra High-Field Imaging; Future Perspectives on High-Field MR

Tumors of the Spine E-Book

Author: Daniel H. Kim,Ung-kyu Chang,Se-Hoon Kim,Mark H. Bilsky

Publisher: Elsevier Health Sciences

ISBN: 1437721648

Category: Medical

Page: 728

View: 8911

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Achieve optimal outcomes for your patients with this new multimedia reference. Organized by tumor then by region, this resource details diagnostic and therapeutic options for primary and malignant spinal tumors. Over 25 key procedures--including minimally invasive surgery--are presented in a concise, stepwise fashion, putting the key information you need right at your fingertips! Over 600 illustrations round out this exhaustive new reference. Keep up to date on the latest advances in diagnosis and therapy with discussions of the latest surgical techniques, including minimally invasive spine surgery. Chapter templating helps you understand the entire procedure as well as key aspects, pearls and pitfalls, before heading into the OR. Have all the information you need to make a diagnosis and plan patient management with oversized, full color clinical photos and line drawings that illustrate key diagnoses and surgical procedures.

Applications of Cell Immobilisation Biotechnology

Author: Viktor Nedovic,Ronnie Willaert

Publisher: Springer Science & Business Media

ISBN: 9781402032295

Category: Science

Page: 573

View: 4809

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Cell immobilisation biotechnology is a multidisciplinary area, shown to have an important impact on many scientific subdisciplines – including biomedicine, pharmacology, cosmetology, food and agricultural sciences, beverage production, industrial waste treatment, analytical applications, biologics production. "Cell Immobilisation Biotechnology" is an outcome of the editors’ intention to collate the extensive and widespread information on fundamental aspects and applications of immobilisation/encapsulation biotechnology into a comprehensive reference work and to provide an overview of the most recent results and developments in this domain. "Cell Immobilisation Biotechnology" is divided into the two book volumes, FOBI 8A and FOBI 8B. The FOBI 8A volume, Fundamentals of Cell Immobilisation Biotechnology, is dedicated to fundamental aspects of cell immobilisation while the present volume, FOBI 8B, Applications of Cell Immobilisation Biotechnology, deals with diverse applications of this technology.

Clinical Neuropathology

Text and Color Atlas

Author: Catherine Haberland, MD

Publisher: Demos Medical Publishing

ISBN: 9781934559529

Category: Medical

Page: 304

View: 8246

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Divided into fourteen chapters, this text and full-color atlas is a complete overview of the pathologic and clinical aspects of neurologic diseases. Clinical Neuropathology is written for practicing neurologists and pathologists, as well as residents and fellows preparing for the neurology and pathology boards. It provides information on the structural alterations of nervous system diseases along with their clinical manifestations. The first two chapters cover the process and goals of the neuropathologic exam and histological reactions particular to the nervous system. Subsequent chapters review major disease categories, with each section containing an overview of pathologic and clinical characteristics in general, a description of the gross and histologic features along with their clinical features, and data on pathogenetic mechanisms. Filled with tables to clarify major points, case histories to provide clinical correlates, and Board-type chapter review questions with answers and explanations, this text will be a valuable addition to all individual and reference libraries. Key Benefits: Almost 600 full color illustrations. Case histories, keyed to images, provide clinical correlation with pathology. Over 90 tables summarizing key points: useful for quick reference and exam preparation. End-of-chapter Board-type questions, with answers and explanations, for self-assessment and exam preparation.

Diffuse Low-Grade Gliomas in Adults

Author: Hugues Duffau

Publisher: Springer

ISBN: 3319554662

Category: Medical

Page: 790

View: 2430

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The second edition of this well-received volume has been revised and updated to reflect the advances in pathological classification and molecular epidemiology of diffuse low-grade gliomas (DLGG) in adults and offers an updated review on individualized therapies. This book presents the latest research pertaining to the diagnosis, genetics, therapy and management of DLGGs. It extensively covers recent research on the natural history of DLGGs and their interaction with the brain and reviews the new diagnostic and therapeutic strategies which increase survival and quality of life of the patient. New topics covered are the management of DLGGs during pregnancy, functional rehabilitation of patients with DLGG and the onco-functional balance in DLGG, among others. The reader will have the opportunity to gain insight in both clinical and basic science aspects of this type of tumor and learn about the application of novel imaging techniques such as diffussion tensor imaging. Edited by a leading expert in the field and authored by a team of recognised specialists, this book is a valuable resource for medical oncologists, neuro-oncologists and neurologists.

Cognitive Plasticity in Neurologic Disorders

Author: Joseph I Tracy,Benjamin M Hampstead,K. Sathian

Publisher: Oxford University Press

ISBN: 0190205466

Category: Medical

Page: 432

View: 2746

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Cognitive Plasticity in Neurologic Disorders describes and specifies the cognitive impact of neuroplastic processes in key neurologic disorders and syndromes. It is set apart from previous works in this area by its emphasis on the changing quality of neurocognition, demonstrating that this dynamic nature emerges from the neuroplastic processes at work in both mild and severe states of brain disease or injury. This resource describes the ways neurological illness or trauma (or attempts to treat patients with such conditions) can trigger neuroplastic mechanisms in the brain, inducing cognitive reorganization and remapping of brain networks. Each chapter shows how the cognitive and behavioral presentation of the disorder mirrors the changing neurobiologic context, and displays the numerous techniques being employed (e.g. behavior and rehabilitation therapies, electrical stimulation, and computer/machine neuromodulation of brain signals) underlying the neurobiology in ways that facilitate adaptive plasticity and cognitive recovery. An important feature of the book involves characterizing the degree to which the mechanistic principles governing neuroplastic responses and cognitive reorganization in the brain have been elucidated, making clear that it is these principles which will allow us to further develop rational rehabilitative therapies, match patients to appropriate treatments, and even begin to predict clinical treatment outcomes.

Caffey's Pediatric Diagnostic Imaging E-Book

Author: Brian D. Coley

Publisher: Elsevier Health Sciences

ISBN: 1455753602

Category: Medical

Page: 1784

View: 9678

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Since 1945, radiologists have turned to Caffey's Pediatric Diagnostic Imaging for the most comprehensive coverage and unparalleled guidance in all areas of pediatric radiology. Continuing this tradition of excellence, the completely revised 12th edition - now more concise yet still complete - focuses on the core issues you need to understand new protocols and sequences, and know what techniques are most appropriate for given clinical situations. "This text will obviously be of great interest not only to radiologists, also to those who work with children including all pediatric specialties. It is also extremely useful in countries with resource poor setting where there is shortage of well-trained radiologists in pediatric specialties." Reviewed by: Yangon Children Hospital on behalf of the Journal of the European Paediatric Neurology Society, January 2014 "This is a thoroughly up-to-date text, divided into manageable topics, at a very reasonable price and I thoroughly recommend it to anyone who needs updating in the field of paediatrics or paediatric imaging." RAD, February 2014 Determine the best modality for each patient with state-of-the art discussions of the latest pediatric imaging techniques. Quickly grasp the fundamentals you need to know through a more precise, streamlined format, reorganized by systems and disease processes, as well as "Teaching Boxes" that highlight key points in each chapter. Apply all the latest pediatric advances in clinical fetal neonatology techniques, technology, and pharmacology. Achieve accurate diagnoses as safely as possible. Increased coverage of MRI findings and newer imaging techniques for all organ systems emphasizes imaging examination appropriateness and safety. Reap the fullest benefit from the latest neuroimaging techniques including diffusion tensor imaging, fMRI, and susceptibility weighted imaging. Keep current with the latest pediatric radiological knowledge and evidence-based practices. Comprehensive updates throughout include new and revised chapters on prenatal imaging; newer anatomic and functional imaging techniques (including advances in cardiac imaging); disease classifications and insights into imaging disease processes; and advanced imaging topics in neurological, thoracoabdominal, and musculoskeletal imaging. Compare your findings to more than 10,000 high-quality radiology images. Access the full text online at Expert Consult including illustrations, videos, and bonus online-only pediatric imaging content.

Clinical Radiation Oncology E-Book

Author: Leonard L. Gunderson,Joel E. Tepper

Publisher: Elsevier Health Sciences

ISBN: 1455726036

Category: Medical

Page: 1660

View: 9156

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With thorough updates throughout, Clinical Radiation Oncology provides the most comprehensive, authoritative, and up-to-date information available for treating patients with cancer. From a multidisciplinary perspective, this new edition, edited by Drs. Leonard L. Gunderson and Joel E. Tepper, examines the therapeutic management of specific disease sites based on both single-modality and combined-modality approaches - providing you with the well-rounded, cutting-edge guidance you need to offer the most effective treatments. A consistent chapter format, full-color design, and access to the full text at www.expertconsult.com make reference fast and easy. It is an ideal resource for mastering the latest, most effective techniques and modalities! Deepen your knowledge with a comprehensive, clinical approach to the scientific foundations of radiation oncology and general oncology as well as state-of-the-art techniques and modalities. Implement a multidisciplinary, "team care" approach to providing intricate treatment plans for patients, often in conjunction with medical oncologists, and surgeons. Broaden your understanding of the basic biology of the disease processes. Examine the therapeutic management of specific disease sites based on single-modality and combined-modality approaches. Quickly and easily find critical information thanks to an easily accessible, full-color design with over 800 color figures that clearly depict treatment techniques. Get broad multimodality perspectives and unique insights from a diverse team of respected editors and contributors –many of whom are new to this edition – affiliated with institutions across North America and internationally Access the fully searchable text anywhere, anytime at www.expertconsult.com, along with references, additional images and tables, video clips and more! Stay current with comprehensive updates throughout that include a new chapter on survivorship issues, and additional video clips on treatments such as prostate and penile cancer brachytherapy. Improve outcomes by providing the most effective treatment for each patient with expanded coverage of new modalities and treatment regimens. Understand and comply with the latest staging guidelines.

Cancer Risk Assessment

Chemical Carcinogenesis, Hazard Evaluation, and Risk Quantification

Author: Ching-Hung Hsu,Todd Stedeford

Publisher: John Wiley & Sons

ISBN: 9781118035122

Category: Science

Page: 856

View: 8215

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With a weight-of-the-evidence approach, cancer risk assessment indentifies hazards, determines dose-response relationships, and assesses exposure to characterize the true risk. This book focuses on the quantitative methods for conducting chemical cancer risk assessments for solvents, metals, mixtures, and nanoparticles. It links these to the basic toxicology and biology of cancer, along with the impacts on regulatory guidelines and standards. By providing insightful perspective, Cancer Risk Assessment helps researchers develop a discriminate eye when it comes to interpreting data accurately and separating relevant information from erroneous.

Neuropsychology of Cancer and Oncology

Author: Dr. Dale L. Johnson, PhD

Publisher: Springer Publishing Company

ISBN: 0826106943

Category: Psychology

Page: 488

View: 5282

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"This book, in both its direct and indirect inferences, points to the need for disease-specific neurocognitive methods in broadly occurring CNS and non-CNS cancers... All in all, this is a beautifully conceptualized book that should be on the bookshelves of many specialists who work in the very challenging field of Oncology."--Carol L. Armstrong, PhD, Children's Hospital of Pennsylvania, Archives of Clinical Neuropsychology Interest in the neurocognitive and sensory impairments resulting from many cancers and their interventions has grown considerably over the past decades as an important aspect of quality of life issues for cancer patients and survivors. The Neuropsychology of Cancer and Oncology features current findings on the neuropsychological effects of these cancers and their treatments along with the most promising neuropsychological and behavioral health interventions available to mitigate these deficits. This edited volume, part of the Contemporary Neuropsychology series, bridges the gap between the knowledge of neuropsychologists, who are grounded in the biological and physiological bases of cognition and behavior but not in pathology, and that of oncologists, who often lack expertise in the neuropsychological aspects of cancer. This text first addresses the biological components and medical care of these cancers, and issues relating to bioimaging. It then discusses the neurological impact of these cancers as they affect different functions, such as memory, learning, and sensory-motor ability, as well as discusses the effects of childhood cancers on neurological development. State-of-the-art neuropsychological and behavioral health interventions are considered, including neuropsychological/cognitive rehabilitation and habituation, pharmacological interventions, and collaborative medical practices. This text is a unique and timely resource for clinical neuropsychologists, clinical psychologists, neurologists, oncologists, oncology nurses, and neurorehabilitation professionals. Key Features: Bridges the gap of knowledge between neuropsychologists and oncologists Explores the most current research on the neuropsychological effects of various cancers and their treatments Provides state-of-the-art information on promising neuropsychological and behavioralñhealth interventions for impairments created by cancers and their treatments Represents a collaboration between some of the foremost scholars and practitioners in neuropsychology and oncology