No-load Mutual Funds

Author: William G. Droms,Peter D. Heerwagen

Publisher: N.A

ISBN: 9780870947124

Category: Mutual funds

Page: 355

View: 4165

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Describes the advantages and limitations of investing in mutual funds, explains how they work, and provides information on the assets, investment philosophy, expense ratios, dividend dates, and return history of a variety of funds

Tea in Health and Disease Prevention

Author: Victor R. Preedy

Publisher: Academic Press

ISBN: 0123849381

Category: Technology & Engineering

Page: 1612

View: 658

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While there have been many claims of the benefits of teas through the years, and while there is nearly universal agreement that drinking tea can benefit health, there is still a concern over whether the lab-generated results are representative of real-life benefit, what the risk of toxicity might be, and what the effective-level thresholds are for various purposes. Clearly there are still questions about the efficacy and use of tea for health benefit. This book presents a comprehensive look at the compounds in black, green, and white teas, their reported benefits (or toxicity risks) and also explores them on a health-condition specific level, providing researchers and academics with a single-volume resource to help in identifying potential treatment uses. No other book on the market considers all the varieties of teas in one volume, or takes the disease-focused approach that will assist in directing further research and studies. Interdisciplinary presentation of material assists in identifying potential cross-over benefits and similarities between tea sources and diseases Assists in identifying therapeutic benefits for new product development Includes coverage and comparison of the most important types of tea - green, black and white

Breaking the Mishap Chain

Human Factors Lessons Learned From Aerospace Accidents and Incidents in Research, Flight Test, and Development

Author: Peter W. Merlin,Gregg A. Bendrick,National Aeronautics and Space Administration

Publisher: Government Printing Office

ISBN: 9780160915635

Category: Science

Page: N.A

View: 6649

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This volume contains a collection of case studies of mishaps involving experimental aircraft, aerospace vehicles, and spacecraft in which human factors played a significant role. In all cases the engineers involved, the leaders and managers, and the operators (i.e., pilots and astronauts) were supremely qualified and by all accounts superior performers. Such accidents and incidents rarely resulted from a single cause but were the outcome of a chain of events in which altering at least one element might have prevented disaster. As such, this work is most certainly not an anthology of blame. It is offered as a learning tool so that future organizations, programs, and projects may not be destined to repeat the mistakes of the past. These lessons were learned at high material and personal costs and should not be lost to the pages of history.

Components of the Language-Ready Brain

Author: Cedric Boeckx,Antonio Benítez-Burraco

Publisher: Frontiers Media SA

ISBN: 2889198936

Category:

Page: N.A

View: 9522

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This volume highlights new avenues of research in the language sciences, and particularly, in the neurobiology of language. The term “language-ready brain” stresses, on the one hand, the importance of a brain-based description of our species’ linguistic capacity, and, on the other, the need to appreciate the crucial role culture plays in shaping the linguistic systems children acquire and adults use. For this reason, the focus is not put on language per se, but on our learning biases and cognitive pre-dispositions toward language. Both brain and culture are considered at two crucial levels of inquiry: phylogeny and ontogeny. In a fast-growing field like the language sciences and specifically, language evolution studies, this book has tried to capture several of the most exciting topics explored currently, sowing seeds for future investigations.

Investing in Mutual Funds

Author: Juliette Fairley

Publisher: Cliff Notes

ISBN: 9780764585173

Category: Business & Economics

Page: 120

View: 3298

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Discusses financial goals, advantages and disadvantages of mutual funds, financial reseach, taxes, and mutual fund services

Current Challenges in Cardiovascular Molecular Diagnostics

Author: Matteo Vatta,Valeria Novelli,Luisa Mestroni,Jeffrey A. Towbin,Carlo Napolitano,Guia Guffanti

Publisher: Frontiers Media SA

ISBN: 2889452816

Category:

Page: N.A

View: 888

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The field of cardiovascular genetics has tremendously benefited from the recent application of massive parallel sequencing technology also referred to as next generation sequencing (NGS). However, along with the discovery of additional genes associated with human cardiac diseases, the analysis of large dataset of genetic information uncovered a much more complex and variegated landscape, which often departs from the comfort zone of the monogenic Mendelian diseases image that clinical molecular geneticists have been well acquainted with for many decades. It is now clear that, in addition to highly penetrant genetic variants, which in isolation are able to recapitulate the full clinical presentation when expressed in animal models, we are now aware that a small but significant fraction of subjects presenting with cardiac muscle diseases such as cardiomyopathies or primary arrhythmias such as long QT syndrome (LQTS), may harbor at least two deleterious variants in the same gene (compound heterozygous) or in different gene (double heterozygous). Although the clinical presentation in subjects with more than one deleterious variant appears to be more severe and with an earlier disease onset, it somehow changes the viewpoint of clinical molecular geneticists whose aim is to identify all possible genetic contributors to a human condition. In this light, the employment in clinical diagnostics of the NGS technology, allowing the simultaneous interrogation of a DNA target spanning from large panel of genes up to the entire genome, will definitely aid at uncovering all such contributors, which will have to be tested functionally to confirm their role in human cardiac conditions. The uncovering of all clinically relevant deleterious changes associated with a cardiovascular disease would probably increase our understanding of the clinical variability commonly occurring among affected family relatives, and potentially provide with unexpected therapeutic targets for the treatment of symptoms related to the presence of “accessory” deleterious genetic variants other than the key molecular culprit. The objective of this Research Topic is to explore the current challenges presenting to the cardiovascular genetics providers, such as clinical geneticists, genetic counselors, clinical molecular geneticists and molecular pathologists involved in the diagnosis, counseling, testing and interpretation of genetic tests results for the comprehensive management of patients affected by cardiovascular genetic disorders.

Dictionary of Acronyms and Technical Abbreviations

For Information and Communication Technologies and Related Areas

Author: Jakob Vlietstra

Publisher: Springer Science & Business Media

ISBN: 1447102630

Category: Computers

Page: 696

View: 3541

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This Dictionary covers information and communication technology (ICT), including hardware and software; information networks, including the Internet and the World Wide Web; automatic control; and ICT-related computer-aided fields. The Dictionary also lists abbreviated names of relevant organizations, conferences, symposia and workshops. This reference is important for all practitioners and users in the areas mentioned above, and those who consult or write technical material. This Second Edition contains 10,000 new entries, for a total of 33,000.

Proceedings of the Third International Symposium on Materials and Sustainable Development

Author: Benmounah Abdelbaki,Brahim Safi,Mohammed Saidi

Publisher: Springer

ISBN: 3319897071

Category: Technology & Engineering

Page: 701

View: 5830

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The third International Symposium on Materials and Sustainable Development ISMSD2017 (CIMDD2017) will include a 2-day Conferences (07 & 08 November). Organized by the Research Unit: Materials, Processes and Environment and University M'hamed Bougara of Boumerdes, this symposium follows the success of CIMDD 2013-2015 and continues the traditions of the highly successful series of International Conferences on the materials, processes and Environment. The Symposium will provide a unique topical forum to share the latest results of the materials and sustainable development research in Algeria and worldwide.

The Little Book of Common Sense Investing

The Only Way to Guarantee Your Fair Share of Stock Market Returns

Author: John C. Bogle

Publisher: John Wiley & Sons

ISBN: 1119404509

Category: Business & Economics

Page: 304

View: 9588

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"The Little Book of Common Sense Investing is the classic guide to getting smart about the market. Legendary mutual fund pioneer John C. Bogle reveals his key to getting more out of investing: low-cost index funds. Bogle describes the simplest and most effective investment strategy for building wealth over the long term: buy and hold, at very low cost, a mutual fund that tracks a broad stock market Index such as the S&P 500. While the stock market has tumbled and then soared since the first edition of Little Book of Common Sense was published in April 2007, Bogle's investment principles have endured and served investors well. This tenth anniversary edition includes updated data and new information but maintains the same long-term perspective as in its predecessor. Bogle has also added two new chapters designed to provide further guidance to investors: one on asset allocation, the other on retirement investing."--Dust jacket.

Handbook of Nanosafety

Measurement, Exposure and Toxicology

Author: Ulla Vogel,Kai Savolainen,Qinglan Wu,Martie van Tongeren,Derk Brouwer,Markus Berges

Publisher: Elsevier

ISBN: 0124166628

Category: Medical

Page: 376

View: 1402

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Handbook of Nanosafety: Measurement, Exposure and Toxicology, written by leading international experts in nanosafety, provides a comprehensive understanding of engineered nanomaterials (ENM), current international nanosafety regulation, and how ENM can be safely handled in the workplace. Increasingly, the importance of safety needs to be considered when promoting the use of novel technologies like ENM. With its use of case studies and exposure scenarios, Handbook of Nanosafety demonstrates techniques to assess exposure and risks and how these assessments can be applied to improve workers' safety. Topics covered include the effects of ENM on human health, characterization of ENM, aerosol dynamics and measurement, exposure and risk assessment, and safe handling of ENM. Based on outcomes from the NANODEVICE initiative, this is an essential resource for those who need to apply current nanotoxicological thinking in the workplace and anyone who advises on nanosafety, such as professionals in toxicology, occupational safety and risk assessment. Multi-authored book, written by leading researchers in the field of nanotoxicology and nanosafety Features state-of-the-art physical and chemical characterization of engineered nanomaterials (ENM) Develops strategies for exposure assessment, risk assessment and risk management Includes practical case studies and exposure scenarios to demonstrate how you can safely use ENM in the workplace

Biology Laboratory Manual

Author: Sylvia S. Mader

Publisher: McGraw-Hill Science, Engineering & Mathematics

ISBN: N.A

Category: Biology

Page: 544

View: 9810

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This laboratory manual is best known for its ability to help students develop critical and creative reasoning skills in investigating science. Dr. Mader provides step-by-step procedures and hands-on activities to help students learn the concepts of biology. This manual covers the entire field of general biology. This manual is color customizable so that instructors can build a manual to fit the way they teach their course.

Civil Engineering Applications of Ground Penetrating Radar

Author: Andrea Benedetto,Lara Pajewski

Publisher: Springer

ISBN: 3319048139

Category: Science

Page: 371

View: 2663

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This book, based on Transport and Urban Development COST Action TU1208, presents the most advanced applications of ground penetrating radar (GPR) in a civil engineering context, with documentation of instrumentation, methods and results. It explains clearly how GPR can be employed for the surveying of critical transport infrastructure, such as roads, pavements, bridges and tunnels and for the sensing and mapping of underground utilities and voids. Detailed attention is also devoted to use of GPR in the inspection of geological structures and of construction materials and structures, including reinforced concrete, steel reinforcing bars and pre/post-tensioned stressing ducts. Advanced methods for solution of electromagnetic scattering problems and new data processing techniques are also presented. Readers will come to appreciate that GPR is a safe, advanced, non destructive and noninvasive imaging technique that can be effectively used for the inspection of composite structures and the performance of diagnostics relevant to the entire life cycle of civil engineering works.

Inhaled Particles

Author: Chiu-sen Wang

Publisher: Elsevier

ISBN: 9780080455013

Category: Technology & Engineering

Page: 214

View: 4857

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Inhaled Particles integrates all that is known about inhaled particles in a unified treatment. It aims to provide a scientific framework essential to a reasonable understanding of inhaled particles. The emphasis is placed on demonstrating the key roles of lung morphology on airflow and particle transport as well as identifying physical and biological factors that influence deposition. Special attention is paid to maintaining consistency of treatment and a balance between theoretical modeling and experimental measurements. The book covers all important aspects of inhaled particles including inhalability, aerosol dispersion, particle deposition, and clearance. It reviews concisely the basic background of lung morphology, respiratory physiology, aerodynamics, and aerosol science pertinent to the subject. Essential aspects of health effects and applications are also included. An easy-to-read, self contained introduction to the field An excellent source of updated research information Useful for students and professionals in aerosol science, environmental health science, occupational hygiene, health physics and biomedical engineering

Extracellular Matrix in Development

Author: Douglas W. DeSimone,Robert Mecham

Publisher: Springer Science & Business Media

ISBN: 3642359353

Category: Science

Page: 253

View: 1793

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Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.

Evolution of the Protein Synthesis Machinery and Its Regulation

Author: Greco Hernández,Rosemary Jagus

Publisher: Springer

ISBN: 3319394681

Category: Science

Page: 564

View: 5927

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The “omics” era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in molecular biology, this text looks into the origins and evolution of the protein synthetic machinery.

Aging

Exploring a Complex Phenomenon

Author: Shamim I. Ahmad

Publisher: CRC Press

ISBN: 1315283875

Category: Medical

Page: 658

View: 7858

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This book is a detailed and comprehensive synthesis of the scientific study of aging. Dozens of contributions from leading scholars review various theories of aging, and molecular, cellular, biochemical and microbial aspects of aging, among just a few of the topics included. Authoritative, wide ranging and thorough, this book will act as a source for experimental design, a comprehensive description of age related diseases, and provide information of the latest molecular theories underlying their causes. Additionally, it will target industries involved in developing anti-aging drugs, post-graduate medical students, and university libraries.

Adult Attachment in Clinical Social Work

Practice, Research, and Policy

Author: Susanne Bennett,Judith Kay Nelson

Publisher: Springer Science & Business Media

ISBN: 9781441962416

Category: Social Science

Page: 271

View: 6957

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The applicability of attachment theory and research to social work and social policy relating to infants and children is well-established. Yet, its usefulness for enhancing the understanding of adults and their needs, both individually and as a group, has been less featured in the attachment literature. Adult Attachment in Clinical Social Work Practice is a wide-ranging look at attachment theory and research, its application to adults, and its natural fit with the social work profession. This edited volume covers the applicability of adult attachment theory to the clinical social work profession’s various domains that include human behavior, practice, policy, research, and social work education. It addresses the broad spectrum of clinical social work, including practice in a variety of public and private settings and with a number of diverse populations, including racial-ethnic groups, gays and lesbians, trauma survivors, and child welfare parents. The book highlights the underemphasized contribution of the social work profession to the development of attachment theory and research.

Epigenetic Modifications Associated with Abiotic and Biotic Stresses in Plants: An Implication for Understanding Plant Evolution

Author: Mahmoud W. Yaish,Heribert Hirt,Barbara Hohn

Publisher: Frontiers Media SA

ISBN: 2889453812

Category:

Page: N.A

View: 1216

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Alterations in gene expression are essential during growth and development phases and when plants are exposed to environmental challenges. Stress conditions induce gene expression modifications, which are associated with changes in the biochemical and physiological processes that help plants to avoid or reduce potential damage resulting from these stresses. After exposure to stress, surviving plants tend to flower earlier than normal and therefore transfer the accumulated epigenetic information to their progenies, given that seeds, where this information is stored, are formed at a later stage of plant development. DNA methylation is correlated with expression repression. Likewise, miRNA produced in the cell can reduce the transcript abundance or even prevent translation of mRNA. However, histone modulation, such as histone acetylation, methylation, and ubiquitination, can show distinct effects on gene expression. These alterations can be inherited, especially if the plants are consistently exposed to a particular environmental stress. Retrotransposons and retroviruses are foreign movable DNA elements that play an important role in plant evolution. Recent studies have shown that epigenetic alterations control the movement and the expression of genes harbored within these elements. These epigenetic modifications have an impact on the morphology, and biotic and abiotic tolerance in the subsequent generations because they can be inherited through the transgenerational memory in plants. Therefore, epigenetic modifications, including DNA methylation, histone modifications, and small RNA interference, serve not only to alter gene expression but also may enhance the evolutionary process in eukaryotes. In this E-book, original research and review articles that cover issues related to the role of DNA methylation, histone modifications, and small RNA in plant transgenerational epigenetic memory were published. The knowledge published on this topic may add new insight on the involvement of epigenetic factors in natural selection and environmental adaptation. This information may also help to generate a modeling system to study the epigenetic role in evolution.