Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3E

Author: Gordon Guyatt

Publisher: McGraw Hill Professional

ISBN: 0071816399

Category: Medical

Page: 864

View: 9469

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The leading guide to the principles and clinical applications of evidence-based medicine--updated with new examples and new chapters Revised and updated to reflect the latest in medical research and evidence-based resources Practical focus and organization to guide clinicians through the fundamentals of using the medical literature to the more advanced strategies and skills for use in patient care, using the key questions to assess any new research: What are the results? How serious is the risk of bias? How do I apply the results to patient care? Updated real-world examples drawn from the medical literature New chapters that reflect the changing complexity of medical research and literature, including genetic association studies, systematic reviews and meta-analyses, network meta-analysis, noninferiority trials, quality improvement, and evidence-based medicine and the theory of knowledge New emphasis on understanding the role of patient preferences and preappraised resources that provide updated evidence and evidence-based recommendations for practice

Evidence-Based Nursing

A Guide to Clinical Practice

Author: Alba DiCenso,Gordon Guyatt,Donna Ciliska

Publisher: Elsevier Health Sciences

ISBN: 0323080901

Category: Medical

Page: 640

View: 3324

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Written in response to numerous requests by nurse practitioners and other graduate faculty for a nursing literature resource, this new two-color book is based on the Users' Guides to the Medical Literature: A Manual for Evidence-Based Practice by Dr. Gordon Guyatt and Dr. Drummond Rennie, published in 2001 by the AMA. Revised for the nursing audience, Evidence-Based Nursing is a reader-friendly, accessible guide that features plentiful examples from the nursing literature and the addition of specific nursing issues such as qualitative research, with direct application for clinical practice. Drs. DiCenso, Ciliska, and Guyatt are three of the leaders in the evidence-based nursing community and command worldwide recognition. Evidence-Based Nursing will enable nurses to frame their clinical questions in a way that will help them find and distinguish between strong and weak evidence; clearly understand study results; weigh the risks and benefits of management options; and apply the evidence to their individual patients to improve outcomes. This is the only book of its kind that helps nurses use the nursing literature effectively to solve patient problems. Three-step approach to dissecting a problem — to help find the best evidence and improve patient care, most questions can be divided into three parts: (1) Are the results valid? (2) What are the results? and (3) How can I apply the results to patient care? Part One - The Basics: Using the Nursing Literature provides a basic approach to the problems faced by nurses when determining optimal care, predicting patient progress, and protecting patients from potentially harmful side effects and includes a literature assessment summary and management recommendations. Part Two - Beyond the Basics: Using and Teaching the Principles of Evidence-Based Nursing expands on Part One, providing concrete examples through the presentation of cases. Two-part organization helps both beginners and those more accomplished at using the nursing literature. Clinical Scenario provides a brief but detailed description of a clinical situation that requires the application of research through a critical thinking process. Using the Guide examines a clinical scenario, and then evaluates the way in which research findings are collected, analyzed, and applied to the resolution of the problem presented in the scenario. Free CD-ROM contains everything found in the book, allowing for electronic outlining, content filtering, full-text searching, and alternative content organizations.

Users' Guides to the Medical Literature

Essentials of Evidence-Based Clinical Practice, Second Edition

Author: Gordon Guyatt,Drummond Rennie,Maureen O. Meade,Deborah J. Cook

Publisher: McGraw Hill Professional

ISBN: 9780071590396

Category: Medical

Page: 380

View: 2924

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The “essential” companion to the landmark Users' Guides to the Medical Literature - completely revised and updated! 5 STAR DOODY'S REVIEW! "This second edition is even better than the original. Information is easier to find and the additional resources that will be available at www.JAMAevidence.com will provide readers with a one-stop source for evidence-based medicine."--Doody's Review Service Evidence-based medicine involves the careful interpretation of medical studies and its clinical application. And no resource helps you do it better-and faster-than Users' Guides to the Medical Literature: Essentials of Evidence-Based Clinical Practice. This streamlined reference distills the most clinically-relevant coverage from the parent Users' Guide Manual into one highly-focused, portable resource. Praised for its clear explanations of detailed statistical and mathematical principles, The Essentials concisely covers all the basic concepts of evidence-based medicine--everything you need to deliver optimal patient care. It's a perfect at-a-glance source for busy clinicians and students, helping you distinguish between solid medical evidence and poor medical evidence, tailor evidence-based medicine for each patient, and much more. Now in its second edition, this carry-along quick reference is more clinically relevant--and more essential--than ever! FEATURES Completely revised and updated with all new coverage of the basic issues in evidence-based medicine in patient care Abundant real-world examples drawn from the medical literature are woven throughout, and include important related principles and pitfalls in using clinical research in patient care decisions Edited by over 60 internationally recognized editors and contributors from around the globe Also look for JAMAevidence.com, a new interactive database for the best practice of evidence based medicine.

Evidence-based Practice in Nursing & Healthcare

A Guide to Best Practice

Author: Bernadette Mazurek Melnyk,Ellen Fineout-Overholt

Publisher: Lippincott Williams & Wilkins

ISBN: 1605477788

Category: Medical

Page: 599

View: 8484

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Bernadette Mazurek Melnyk and Ellen Fineout-Overholt are creators of the ARCC (Advancing Research and Clinical practice through close Collaboration) Model, an innovative strategy for implementing and sustaining evidence-based practice in healthcare systems. The ARCC Model is cited as an exemplar of education in evidence-based practice in the Board on Health Care Services and the Institute of Medicine's book, Health Professions Education: A Bridge to Quality. "McInyk and Fineout-Overholt's book should be required reading in all graduate programs. Their text has provided a blueprint for the future of nursing practice and a rigorously substantiated and clearly described means for clinicians, educators, and administrators to participate in improving quality of care." Janet D. Allan, PhD, RN, FAAN Dean and Professor University of Maryland School of Nursing "Evidence-based Practice in Nursing & Healthcare: A Guide to Best Practice has been instrumental in developing a culture of evidence-based practice at Barnes-Jewish Hospital. It is fundamental to our curriculum provided to all levels of staff, from new graduate nurses to the highest levels of hospital leadership." Dr. Patricia Potter, RN, PhD, FAAN, Dr. Gail Rea, RN, PhD, CNE, Dr. Karen Balakas, RN, PhD, CNE, Jennifer Williams, MSN, RN, ACNS-BC, Elizabeth Pratt, MSN, RN, ACNS-BC Evidence Equals Excellence group at Barnes-Jewish Hospital and Barnes-Jewish School of Nursing at Goldfarb Evidence-based Practice in Nursing & Healthcare: A Guide to Best Practice is an exemplary text that spans the continuum of nursing evidence to support best practice. Utilizing this text with undergraduate, RN to BSN, and graduate nursing students, it is the ONLY text that demonstrates how to retrieve, read, and analyze evidence whether it is published as an individual study, systematic review, meta-analysis, best practice guideline, or outcomes management report. Students learn how to utilize multiple complex databases and websites as they move through each chapter. And, they experience dissemination of evidence through the development of presentations, publications, posters, and grants. This is truly a remarkable book that embraces evidence as the basis for nursing practice and patient-centered care and safety. Having used this text with more than 1000 students over the past five years, I can honestly say that I have found no other text that facilitates learning and development of clinical judgment that is grounded in valid, reliable, and applicable evidence. This is a keeper! Alice E. Dupler, JD, APRN-BC Clinical Associate Professor Washington State University College of Nursing "I have used the book since I developed the Evidence-based Practice course for our College of Nursing in Fall 2007. It was the first course of its kind at Indiana State University. It has been well received and the preferred course for all nursing graduate students for completion of their final scholarly projects. The text was essential in developing the course and provides the foundation and guidance that the students need to develop their Evidence Based Practice projects...the students love the text!" Susan Eley PhD, RN, FNP-BC Assistant Professor Director FNP Program Indiana State University

The Rational Clinical Examination: Evidence-Based Clinical Diagnosis

Author: David Simel,Drummond Rennie

Publisher: McGraw Hill Professional

ISBN: 9780071590310

Category: Medical

Page: 732

View: 680

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The ultimate guide to the evidence-based clinical encounter "This book is an excellent source of supported evidence that provides useful and clinically relevant information for the busy practitioner, student, resident, or educator who wants to hone skills of physical diagnosis. It provides a tool to improve patient care by using the history and physical examination items that have the most reliability and efficiency."--Annals of Internal Medicine "The evidence-based examination techniques put forth by Rational Clinical Examination is the sort that can be brought to bear on a daily basis – to save time, increase confidence in medical decisions, and help decrease unnecessary testing for conditions that do not require absolute diagnostic certainty. In the end, the whole of this book is greater than its parts and can serve as a worthy companion to a traditional manual of physical examination."--Baylor University Medical Center (BUMC)Proceedings 5 STAR DOODY'S REVIEW! "Physical diagnosis has been taught to every medical student but this evidence-based approach now shows us why, presenting one of medicine's most basic tenets in a new and challenging light. The format is extraordinary, taking previously published material and updating the pertinent evidence since the initial publication, affirming or questioning or refining the conclusions drawn from the data. "This is a book for everyone who has studied medicine and found themselves doubting what they have been taught over the years, not that they have been deluded, but that medical traditions have been unquestionably believed because there was no evidence to believe otherwise. The authors have uncovered the truth. "This extraordinary, one-of-a-kind book is a valuable addition to every medical library."--Doody's Review Service Completely updated with new literature analyses, here is a uniquely practical, clinically relevant approach to the use of evidence in the content of physical examination. Going far beyond the scope of traditional physical examination texts, this invaluable resource compiles and presents the evidence-based meanings of signs, symptoms, and results from physical examination maneuvers and other diagnostic studies. Page after page, you'll find a focus on actual clinical questions and presentations, making it an incomparably practical resource that you'll turn to again and again. Importantly, the high-yield content of The Rational Clinical Examination is significantly expanded and updated from the original JAMA articles, much of it published here for the first time. It all adds up to a definitive, ready-to-use clinical exam sourcebook that no student or clinician should be without. FEATURES Packed with updated, new, and previously unpublished information from the original JAMA articles Standardized template for every issue covered, including: Case Presentation; Why the Issue Is Clinically Important; Research and Statistical Methods Used to Find the Evidence Presented; The Sensitivity and Specificity of Each Key Result; Resolution of the Case Presentation; and the Clinical Bottom Line Completely updated with all-new literature searches and appraisals supplementing each chapter Full-color format with dynamic clinical illustrations and images Real-world focus on a specific clinical question in each chapter, reflecting the way clinicians approach the practice of evidence-based medicine More than 50 complete chapters on common and challenging clinical questions and patient presentations Also available: JAMAevidence.com, a new interactive database for the best practice of evidence based medicine

Users' Guides to the Medical Literature: Essentials of Evidence-Based Clinical Practice 3e

Author: Gordon Guyatt,Drummond Rennie,Maureen O. Meade,Deborah J. Cook

Publisher: McGraw Hill Professional

ISBN: 0071808728

Category: Medical

Page: 545

View: 3462

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The streamlined companion to the classic Users' Guides to the Medical Literature--fully updated and revised This compact guide condenses the most clinically relevant content of the landmark Users' Guides to the Medical Literature to help you incorporate evidence-based medicine into your practice. You will learn the principles of evidence-based medicine, how your practice can benefit from the constant stream of new medical literature, and how to differentiate good medical evidence from bad. This edition includes several new chapters and a new emphasis on the role of patient preferences and preappraised resources. A comprehensive online resource for teaching, learning, and applying evidence-based medicine to improve patient care.

Is evidence-based psychiatry ethical?

Author: Mona Gupta

Publisher: OUP Oxford

ISBN: 0191028312

Category: Medical

Page: 192

View: 2029

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Rated as one of the top 15 breakthroughs in medicine over the last 150 years, evidence-based medicine (EBM) has become highly influential in medicine. Put simply, EBM promotes a seemingly irrefutable, principle: that decision-making in medical practice should be based, as much as possible, on the most up-to-date research findings. EBM has been particularly popular within psychiatry, a field that is haunted by a legacy of controversial interventions. For advocates, anchoring psychiatric practice in research data makes psychiatry more scientific valid and ethically legitimate. Few, however, have questioned whether EBM, a concept pioneered by those working in other areas of medicine, can be applied to psychiatric disorders. In this groundbreaking book, the Canadian psychiatrist and ethicist Mona Gupta analyzes the basic assumptions of EBM, and critically examines their applicability to psychiatry. By highlighting the basic ethical tensions between psychiatry and EBM, the author addresses the fundamental and controversial question - should psychiatrists practice evidence-based medicine at all?

Evidence-based Rehabilitation

A Guide to Practice

Author: Mary C. Law,Joy MacDermid

Publisher: SLACK Incorporated

ISBN: 9781556427688

Category: Medical

Page: 434

View: 4116

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This text provides the most up-to-date information on evidence-based practice, the concepts underlying evidence-based practice, and implementing evidence into the rehabilitation practice. This text is organized by the steps of the process of evidence-based practice--introduction to evidence-based practice, finding the evidence, assessing the evidence, and using the evidence.

Care at the Close of Life: Evidence and Experience

Author: Stephen J. McPhee,Margaret A. Winker,Michael W. Rabow,Steven Z. Pantilat,Amy J. Markowitz

Publisher: McGraw Hill Professional

ISBN: 9780071637961

Category: Medical

Page: 608

View: 8951

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The world's leading source of evidence-based guidance on caring for patients at the end of life. Featuirng the content of the world's most widely read medical journal, plus completely new, never-before-published content. Perfect for medical students, trainees, and clinicians alike. Market / Audience Medical students: 18000/yr US, 250,000 global NP and PA students: 25,000/yr US, 50,000+ global IM and FP residents: 30,000 US, 60,000 global IM and FP clinicians: 140,000 US, 300,000+ global Palliative medicine: 3000 US Oncology: 20,000 US, 60,000 global Social workers About the Book In the tradition of the User's Guides to the Medical Literature, and The Rational Clinical Examination, JAMA/Care at the Close of Life is based on a widely successful series of articles appearing over the course of the last ten years in JAMA, the world's most widely read medical journal. The series is directed by Stephen McPhee, a leading authoriity of end of life care, and the chief editor of our market leading Current Medical Diagnosis and Treatment text. The articles in the series cover fundamental topics and challenges in caring for patients who have been given a terminal diagnosis. Featuring a strong focus on evidence-based medicine, and organized by clinical cases, the articles are widely read by faculty, medical students, and clinicians who, frankly, have not been given a solid educational experience on this very important medical issue. The book will be physically modeled after The Rational Clinical Examination, in a full color format that highlights the clinical cases. It will be well suited for use as an required or recommended textbook for medical, PA, and NO students, and as a clinical reference text for trainees and practicing physicians and nurses. Key Selling Features Based on highy regarded content from the world's most widely read medical journal All content is completely updated, and extensive new, never-before-published content has been added Case-based, and evidence-based, so its a perfect fit for the way medical students and residents like to learn Focuses on practical, real-world issues for primary care physicians, and avoids esoteric issues of interest only to specialists in palliative care Full color format, modeled after the highly regarded Rational Clinical Examination Includes multimedia materials available on line: Power Point slides for teaching, and video interviews with patients in end-of-life care, so that faculty and students get supplemental resources for learning the art and science of care at the end of life Evidence-based guidance from the world's leading medical journal, on a critical topic that has been neglected in medical education and training until recently. Author Profile JAMA is the world's most widely read medical journal, and has a reputation for excellence in evidence-based medicine. Stephen McPhee has high visbility on account of his editorship of CMDT, and for his driving role in enhancing end of life care in medical education and training programs. He is: Professor of Medicine, UCSF School of Medicine, San Francisco CA

Designing Clinical Research

Author: Stephen B. Hulley,Steven R. Cummings,Warren S. Browner,Deborah G. Grady,Thomas B. Newman

Publisher: Lippincott Williams & Wilkins

ISBN: 1469840545

Category: Medical

Page: 378

View: 9761

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Designing Clinical Research sets the standard for providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This product incorporates current research methodology--including molecular and genetic clinical research--and offers an updated syllabus for conducting a clinical research workshop. Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focused research questions and details the steps through all the elements of study design, data collection, quality assurance, and basic grant-writing.

Multicultural Perspectives In Social Work Practice with Families, 3rd Edition

Author: Elaine P. Congress, MSSW, DSW,Manny J. Gonzalez, DSW

Publisher: Springer Publishing Company

ISBN: 082610830X

Category: Social Science

Page: 408

View: 8659

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Multicultural Perspectives in Social Work Practice with Families is in its thirdedition and continues to expand the depth and breadth with which culturemay be understood and the impact of culture in working with families.Congress, Gonzalez, and their contributors have updated this text to includea focus on evidence-based practice, 10 additional chapters, revision of avaluable assessment tool, and a culturagram. This book clearly is an essentialresource for social workers committed to culturally sensitive practice."--Journal of Teaching in Social Work Encompassing the most current issues faced by multicultural families across the lifespan and the social workers who serve them, this popular textbook contains ten new chapters and provides content that has been significantly expanded throughout. These new and reconceived chapters offer professors and social work graduate students a broader and more comprehensive take on the key issues that arise when treating families from diverse cultural backgrounds and current, evidence-based models for assessment and treatment. New chapters include: Evidence-based models of care for ethnically-diverse families Practice with Asian-American families Practice with Native American and indigenous families Practice with Hispanic families Practice with Arab families Practice with adolescents Practice with families when there is risk of suicide Practice with families dealing with substance use and abuse Practice with families around health issues Legal issues with immigrants Contributors to the text are leaders in the field of multicultural issues that encompass a wide range of racial and ethnic populations. Updated case studies, vignettes, and statistical data illustrate the book's content.

How to Read a Paper

The Basics of Evidence-Based Medicine

Author: Trisha Greenhalgh

Publisher: John Wiley & Sons

ISBN: 111880113X

Category: Medical

Page: 288

View: 9297

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The best-selling introduction to evidence-based medicine In a clear and engaging style, How to Read a Paper demystifies evidence-based medicine and explains how to critically appraise published research and also put the findings into practice. An ideal introduction to evidence-based medicine, How to Read a Paper explains what to look for in different types of papers and how best to evaluate the literature and then implement the findings in an evidence-based, patient-centred way. Helpful checklist summaries of the key points in each chapter provide a useful framework for applying the principles of evidence-based medicine in everyday practice. This fifth edition has been fully updated with new examples and references to reflect recent developments and current practice. It also includes two new chapters on applying evidence-based medicine with patients and on the common criticisms of evidence-based medicine and responses. How to Read a Paper is a standard text for medical and nursing schools as well as a friendly guide for everyone wanting to teach or learn the basics of evidence-based medicine.

Tietz Textbook of Clinical Chemistry and Molecular Diagnostics - E-Book

Author: Carl A. Burtis,Edward R. Ashwood,David E. Bruns

Publisher: Elsevier Health Sciences

ISBN: 1455759422

Category: Medical

Page: 2256

View: 9295

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As the definitive reference for clinical chemistry, Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 5th Edition offers the most current and authoritative guidance on selecting, performing, and evaluating results of new and established laboratory tests. Up-to-date encyclopedic coverage details everything you need to know, including: analytical criteria for the medical usefulness of laboratory procedures; new approaches for establishing reference ranges; variables that affect tests and results; the impact of modern analytical tools on lab management and costs; and applications of statistical methods. In addition to updated content throughout, this two-color edition also features a new chapter on hemostasis and the latest advances in molecular diagnostics. Section on Molecular Diagnostics and Genetics contains nine expanded chapters that focus on emerging issues and techniques, written by experts in field, including Y.M. Dennis Lo, Rossa W.K. Chiu, Carl Wittwer, Noriko Kusukawa, Cindy Vnencak-Jones, Thomas Williams, Victor Weedn, Malek Kamoun, Howard Baum, Angela Caliendo, Aaron Bossler, Gwendolyn McMillin, and Kojo S.J. Elenitoba-Johnson. Highly-respected author team includes three editors who are well known in the clinical chemistry world. Reference values in the appendix give you one location for comparing and evaluating test results. NEW! Two-color design throughout highlights important features, illustrations, and content for a quick reference. NEW! Chapter on hemostasis provides you with all the information you need to accurately conduct this type of clinical testing. NEW! Six associate editors, Ann Gronowski, W. Greg Miller, Michael Oellerich, Francois Rousseau, Mitchell Scott, and Karl Voelkerding, lend even more expertise and insight to the reference. NEW! Reorganized chapters ensure that only the most current information is included.

Registries for Evaluating Patient Outcomes

A User’s Guide

Author: Agency for Healthcare Research and Quality/AHRQ

Publisher: Government Printing Office

ISBN: 1587634333

Category: Medical

Page: 356

View: 2523

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This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.

Health Services Research and Evidence-Based Medicine in Hand Surgery, An Issue of Hand Clinics,

Author: Jennifer Waljee

Publisher: Elsevier Health Sciences

ISBN: 0323320325

Category: Medical

Page: 145

View: 2178

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This issue focuses on the integration of health services research into clinical practice. It provides an overview of the field of health services research for the practicing hand surgeon and highlights pertinent topics that can inform clinical care in any practice setting.

Physician Assistant: A Guide to Clinical Practice E-Book

Author: Ruth Ballweg,Darwin Brown,Daniel Vetrosky

Publisher: Elsevier Health Sciences

ISBN: 145572310X

Category: Medical

Page: 792

View: 8222

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Prepare for every stage of your physician assistant career with Physician Assistant: A Guide to Clinical Practice, 5th Edition - the one text that takes you from your PA coursework through clinical practice! Concise, easy to read, and highly visual, this all-in-one resource by Ruth Ballweg, Edward M. Sullivan, Darwin Brown, and Daniel Vetrosky delivers the current, practical guidance you need to know to succeed in any setting. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Master all the core competencies you need to know for certification or recertification. Navigate today's professional challenges with new chapters on NCCPA Specialty Recognition; Communication Issues; the Electronic Health Record; Patient Safety and Quality of Care; Population-Based Practice; and Physician Assistants and Supervision. Meet ARC-PA accreditation requirements with coverage of key topics such as Student Safety in Clinical Settings, Health Care Delivery Systems, Population-Based Practice, and Mass Casualties/Disasters. Keep up with the PA competencies that are endorsed by the AAPA, PAEA, NCCPA, and ARC-PA. Master key concepts and clinical applications thanks to a succinct, bulleted writing style; convenient tables; practical case studies; and clinical application questions throughout. Retain what you’ve learned and easily visualize every aspect of clinical practice with a new full-color design and illustrations throughout. Explore global options with expanded coverage of physician assistants in international medicine.

A User's Guide to the Brain

Perception, Attention, and the Four Theaters of the Brain

Author: John J. Ratey,Albert M. Galaburda

Publisher: Vintage

ISBN: 0375701079

Category: Psychology

Page: 404

View: 1825

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An accessible resource to the structure and chemistry of the brain explains how its systems shape our perceptions, feelings, and behaviors, while outlining the author's theory of the dynamic interaction between the four major brain systems. Reprint. 25,000 first printing.

Sod Seventy!

The Guide to Living Well

Author: Muir Gray

Publisher: Bloomsbury Publishing

ISBN: 1472918983

Category: Self-Help

Page: 224

View: 4093

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Many of the problems older people suffer from have, as their underlying cause, a fundamental loss of fitness. Others are caused by preventable diseases (with these even being preventable after the age of seventy) and, broadly speaking, from the wrong approach to life, influenced by negative social pressures. This book – uniquely targeted at the 60–75 demographic – tells you what steps you can take in late middle age to give you the best chance of living a long, healthy and fulfilling later life. Keep fit, keep the brain going, and with a spot of good fortune you can be living a rewarding, active life into your nineties and beyond. This book – part exercise book, part manifesto for a happier, healthier life – tells you how.