The FDA and Worldwide Quality System Requirements Guidebook for Medical Devices

Author: Amiram Daniel

Publisher: ASQ Quality Press

ISBN: 0873897404

Category: Medical

Page: 304

View: 9787

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How have recent changes in domestic and international regulations affected quality management in the development and marketing of medical devices in the US and abroad? Consultants Daniel and Kimmelman take a close look at the Quality System Regulation (QsReg), the ISO 13485: 2003 standard and the ISO/TR 14969: 2004 guidance document as well as a number of US Food and Drug Administration (FDA) and Global Harmonization Task Force (GHTF) guidance documents. The authors provide extensive commentary and notes an update their material to include such topics as the incorporation of principles of risk management into the medical device organizations' quality management systems (QMSs) and considerations of combination products. Daniel and Kimmelman include full coverage of the QSReg requirements, descriptions of comparable requirements in the ISO documents, excerpts of the FDA's responses to the QSReg preamble and excerpts from FDA guidance documents related to QMSs.

The Certified Pharmaceutical GMP Professional Handbook, Second Edition

Author: Mark Allen Durivage

Publisher: ASQ Quality Press

ISBN: 0873899334

Category: Business & Economics

Page: 516

View: 9177

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The purpose of this handbook is to assist individuals for the Certified Pharmaceutical Good Manufacturing Practices Professional (CPGP) examination and provide a reference for the practitioner. The second edition reflects the Body of Knowledge which was updated in 2015. This edition has also incorporated additional information including updated references. The updates reflect the current trends and expectations of the evolving pharmaceutical industry driven by consumer expectations and regulatory oversight. This handbook covers compliance with good manufacturing practices (GMPs), as regulated and guided by national and international agencies for the pharmaceutical industry. It covers finished human and veterinary drugs and biologics, and combination devices, as well as their component raw materials (including active pharmaceutical ingredients (APIs) and excipients), and packaging and labeling operations.

Handbook of Investigation and Effective CAPA Systems, Second Edition

Author: José Rodríguez-Pérez

Publisher: ASQ Quality Press

ISBN: 0873899261

Category: Business & Economics

Page: 234

View: 6875

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Understanding and improving the CAPA system as a whole is the focal point of this book, the only of its kind dealing exclusively with this critical system within highly regulated industries. Features include: Information about the importance of the CAPA system within the quality system for the medical products regulated industry. Fully updated with current versions of regulations (U.S. FDA, EU, ISO 13485, and so on), and a new section covers the regulatory expectation of customer complaint investigations. Investigation and CAPA elements of the 2015 revision of the ISO 9001 standard. New coverage on the investigation plan and the new U.S. FDA quality metric guidance, as well as a section discussing the tight relationship between CAPAs and FMEA. A new chapter fully devoted to human errors and human factors, and their impact in the investigation and CAPA system. Discussion of a dozen of the most common pitfalls commonly encountered in the investigation and CAPA world of regulated companies. An example of an investigation and CAPA expert certification program being used for many companies. Forms and examples of the different elements (investigation report, root causes checklist, human error investigation, CAPA plan, and so on) covered in the book. Fully usable forms are also included in the companion CD in Microsoft Word format. While the first edition of this book was aimed solely at the FDA-regulated industry, the title of this second edition reflects the importance of the investigation/root cause analysis stage as the necessary preceding step of any effective corrective and preventive action system. Investigation and CAPA are concepts used in many sectors besides the FDA-regulated industry, such as: automotive, electronics, aerospace, telecommunications, process industry, and many more. This book will become an essential reference for those in these other industries.

Statistical Process Control for the FDA-Regulated Industry

Author: Manuel E. Pena-Rodriguez

Publisher: ASQ Quality Press

ISBN: 0873898524

Category: Business & Economics

Page: 204

View: 4381

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The focus of this book is to understand and apply the different SPC tools in a company regulated by the Food and Drug Administration (FDA): those that manufacture pharmaceutical products, biologics, medical devices, food, cosmetics, and so on. The book is not intended to provide an intensive course in statistics; instead, it is intended to provide a how-to guide about the application of the diverse array of statistical tools available to analyze and improve the processes in an organization regulated by FDA. This book is aimed at engineers, scientists, analysts, technicians, managers, supervisors, and all other professionals responsible to measure and improve the quality of their processes. Although the examples and case studies presented throughout the book are based on situations found in an organization regulated by FDA, the book can also be used to understand the application of those tools in any type of industry. Readers will obtain a better understanding of some of the statistical tools available to control their processes and be encouraged to study, with a greater level of detail, each of the statistical tools presented throughout the book. The content of this book is the result of the author’s almost 20 years of experience in the application of statistics in various industries, and his combined educational background of engineering and law that he has used to provide consulting services to dozens of FDA-regulated organizations.

The FDA and Worldwide Quality System Requirements Guidebook for Medical Devices

Author: N.A

Publisher: Asq Press

ISBN: N.A

Category: Law

Page: 210

View: 5551

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This book provides essential information regarding the new FDA regulation for medical devices and international quality system requirements (ISO 9001 and ISO/DIS 13485:1996). Icons quickly establish the differences and relationship between FDA regulation, the ISO 9001 standard, FDA guidance, and the Global Harmonization Task Force (GHTF) guidance. In addition, the end of each subsection includes blank pages for your notes. This book allows manufacturers to establish a single quality system that satisfies world requirements.

Human Error Reduction in Manufacturing

Author: José Rodríguez-Pérez

Publisher: ASQ Quality Press

ISBN: 0873899733

Category: Business & Economics

Page: 268

View: 7587

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For many years, we considered human errors or mistakes as the cause of mishaps or problems. In the manufacturing industries, human error, under whatever label (procedures not followed, lack of attention, or simply error), was the conclusion of any quality problem investigation. The way we look at the human side of problems has evolved during the past few decades. Now we see human errors as the symptoms of deeper causes. In other words, human errors are consequences, not causes. The basic objective of this book is to provide readers with useful information on theories, methods, and specific techniques that can be applied to control human failure. It is a book of ideas, concepts, and examples from the manufacturing sector. It presents a comprehensive overview of the subject, focusing on the practical application of the subject, specifically on the human side of quality and manufacturing errors. In other words, the primary focus of this book is human failure, including its identification, its causes, and how it can be reasonably controlled or prevented in the manufacturing industry setting. In addition to including a detailed discussion of human error (the inadvertent or involuntary component of human failure), a chapter is devoted to analysis and discussion related to voluntary (intentional) noncompliance. Written in a direct style, using simple “industry” language with abundant applied examples and practical references, this book’s insights on human failure reduction will improve individual, organizational, and social well-being.

Books in Print

Author: N.A

Publisher: N.A

ISBN: N.A

Category: American literature

Page: N.A

View: 7907

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Books in print is the major source of information on books currently published and in print in the United States. The database provides the record of forthcoming books, books in-print, and books out-of-print.

Struma

Author: Johannes Köbberling,Caroline R. Pickardt

Publisher: Springer-Verlag

ISBN: 3642883133

Category: Medical

Page: 211

View: 6200

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Untersuchungen über die radioaktiven Substanzen

Author: Marie Curie

Publisher: BoD – Books on Demand

ISBN: 3845722223

Category: Science

Page: 144

View: 5686

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Marie Sklodowska Curie, Trägerin des Nobelpreises für Physik und für Chemie, untersuchte die von Henri Becquerel beobachtete Strahlung von Uranverbindungen. Gemeinsam mit ihrem Mann Pierre entdeckte sie das Radium und das Polonium und prägte den Begriff „radioaktiv“. Ihre Forschungsergebnisse fasste sie in ihrer hier vorliegenden Dissertation zusammen, die innerhalb eines Jahres in fünf Sprachen übersetzt wurde. Sorgfältig bearbeiteter Nachdruck der deutschsprachigen Ausgabe aus dem Jahr 1904.

Ernährung für Dummies

Author: Carol Ann Rinzler

Publisher: Wiley-VCH

ISBN: 9783527700196

Category: Health & Fitness

Page: 320

View: 2548

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Ist Cholesterin immer "schlecht"? Hilft Brokkoli gegen Krebs? Wie gehe ich mit Lebensmittelallergien um? Welche Diät ist gesund? Wenn Sie solche Fragen quälen, sollten Sie in dieses Buch schauen. Carol Ann Rinzler gibt Ihnen einen fundierten Überblick über alles, was Sie zum Thema Ernährung wissen sollten, und natürlich auch viele Tipps für's Kochen. Kommen Sie also mit auf einen kleinen Verdauungsspaziergang und sehen Sie, wie die Nährstoffe in Ihrem Körper arbeiten! Sie erfahren: * Worauf Sie bei Ihrer Ernährung achten sollten * Was Sie mit Ihrer Nahrung alles aufnehmen * Wofür all die Kohlenhydrate, Proteine, Mineralien und was es sonst noch so gibt gut sind * Welche Nahrung denn wirklich "gesund" ist * Was passiert, wenn Sie Lebensmittel kochen, einfrieren etc. * Warum Nahrung auch Medizin ist

Scale-up

Modellübertragung in der Verfahrenstechnik

Author: Marko Zlokarnik

Publisher: John Wiley & Sons

ISBN: 3527660461

Category: Science

Page: 295

View: 7241

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Die Übertagung von Verfahren aus dem Labor-bzw. dem Techni-kumsmaßstab in den industriellen maßstab einer Produktiosanlage ist eine der wichtigsten ingenieurstechnischen Aufgaben in der chemischen Industrie. Die einzige zuverlässige Methode dazu basiert auf der Darstellung von Versuchsergebnissen im zutreffenden dimensions-analytischen Raum, der sich als maßstabsinvariant erweist. Das Buch ist in zwei Teile gegliedert: In der ersten Hälfte werden die vertiefte mathematische Vorkenntnisse dieses Themengebiet näherzubringen. Diskutiert werden die Grundlagen der Dimensionsanalyse, die Behandlung von temperaturabhängigen und von rheologischen Stoffwerten und die Modellübertragung bei Nichtverfügbarkeit von Modellstoffsystemen, sowie bei partieller Ähnlichkeit/ All dies wird dem leser anhand von 20 modernen Beispielen aus der heutigen verfahrenstechnischcen Praxis illustriert, der sich mit 25 in dieser Auflage neu hinzugekommenen Übungsaufgaben sein Verständnis aktive erarbeiten und anhand der Lösungen kontrollieren kann. Im zweitem Teil des Buches werden die einzelnen verfahrenstechnischen Grundoperationen aus den Bereichen mechanische, thermische und chemische Verfahrenstechnik aus der Sicht der Dimensionsanalyse und der Modellübertragung beispielhaft behandelt, und es werden für jede Operation die Maßstabsübertragungsregeln vorgestellt und diskutiert. Das vorliegende Buch wendet sich dementsprechend an Studenten wie auch bereits auf dem gebiet tätige Ingenieure, Chemiker und Verfahrenstechniker.