The Emperor of All Maladies

A Biography of Cancer

Author: Siddhartha Mukherjee

Publisher: Simon and Schuster

ISBN: 1439170916

Category: History

Page: 573

View: 4068

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An assessment of cancer addresses both the courageous battles against the disease and the misperceptions and hubris that have compromised modern understandings, providing coverage of such topics as ancient-world surgeries and the development of present-day treatments. Reprint. Best-selling winner of the Pulitzer Prize. Includes reading-group guide.

The Emperor of All Maladies

A Biography of Cancer

Author: Siddhartha Mukherjee

Publisher: Simon and Schuster

ISBN: 1439181713

Category: History

Page: 592

View: 8359

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Winner of the Pulitzer Prize, and now a documentary from Ken Burns on PBS, The Emperor of All Maladies is a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave may have cut off her diseased breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

The Laws of Medicine

Field Notes from an Uncertain Science

Author: Siddhartha Mukherjee

Publisher: Simon and Schuster

ISBN: 147678485X

Category: Medical

Page: 96

View: 6934

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Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all. Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.

The Gene

An Intimate History

Author: Siddhartha Mukherjee

Publisher: Simon and Schuster

ISBN: 1476733538

Category: Medical

Page: 608

View: 6214

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THE #1 NEW YORK TIMES BESTSELLER A New York Times Notable Book A Washington Post and Seattle Times Best Book of the Year From the Pulitzer Prize-winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).

Summary & Study Guide - The Emperor of All Maladies

A Biography of Cancer

Author: Lee Tang

Publisher: LMT Press via PublishDrive

ISBN: 0994764073

Category: Health & Fitness

Page: 102

View: 7943

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You will never look at cancer the same. The must-read summary of "The Emperor of All Maladies: A Biography of Cancer" by Siddhartha Mukherjee. This book chronicles a fascinating "biography" of cancer—from its first documented appearance five thousand years ago through the battles in the 20th century to cure, control, and subdue it, to a new understanding of its biology. It recounts the centuries of discoveries, successes, and failures in the cat and mouse battle against cancer, bringing cancer research and cancer biology to the lay public. This guide includes: * Book Summary—The summary helps you understand the key ideas and recommendations. * Online Videos—On-demand replay of public lectures, and seminars on the topics covered in the chapter. Value-added of this guide: * Save time * Understand key concepts * Expand your knowledge Read this summary to get an informative overview of the evolution of healthcare and health research, in addition to the specific history of cancer.

The Noonday Demon

An Atlas Of Depression

Author: Andrew Solomon

Publisher: Simon and Schuster

ISBN: 145161103X

Category: Biography & Autobiography

Page: 576

View: 7561

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The author offers a look at depression, drawing on his own battle with the illness and interviews with fellow sufferers, researchers, and doctors to assess the disease's complexities, causes, symptoms, and available therapies.

Long for This World

The Strange Science of Immortality

Author: Jonathan Weiner

Publisher: Harper Collins

ISBN: 0062000217

Category: Science

Page: 320

View: 9563

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“[A] searching and surprisingly witty look at the scientific odds against tomorrow.” —Timothy Ferris Jonathan Weiner—winner of the Pulitzer Prize, the National Book Critics Circle Award, and the Los Angeles Times Book Prize, and one of the most distinguished popular science writers in America—examines “the strange science of immortality” in Long for This World. A fast-paced, sure-to-astonish scientific adventure from “one of our finest science journalists” (Jonah Lehrer), Weiner’s Long for This World addresses the ageless question, “Is there a secret to eternal youth?” And has it, at long last, been found?

The Cancer Chronicles

Unlocking Medicine's Deepest Mystery

Author: George Johnson

Publisher: Vintage

ISBN: 0385349718

Category: Medical

Page: 304

View: 7503

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When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way—an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease. Deftly excavating and illuminating decades of investigation and analysis, he reveals what we know and don’t know about cancer, showing why a cure remains such a slippery concept. We follow him as he combs through the realms of epidemiology, clinical trials, laboratory experiments, and scientific hypotheses—rooted in every discipline from evolutionary biology to game theory and physics. Cogently extracting fact from a towering canon of myth and hype, he describes tumors that evolve like alien creatures inside the body, paleo-oncologists who uncover petrified tumors clinging to the skeletons of dinosaurs and ancient human ancestors, and the surprising reversals in science’s comprehension of the causes of cancer, with the foods we eat and environmental toxins playing a lesser role. Perhaps most fascinating of all is how cancer borrows natural processes involved in the healing of a wound or the unfolding of a human embryo and turns them, jujitsu-like, against the body. Throughout his pursuit, Johnson clarifies the human experience of cancer with elegiac grace, bearing witness to the punishing gauntlet of consultations, surgeries, targeted therapies, and other treatments. He finds compassion, solace, and community among a vast network of patients and professionals committed to the fight and wrestles to comprehend the cruel randomness cancer metes out in his own family. For anyone whose life has been affected by cancer and has found themselves asking why?, this book provides a new understanding. In good company with the works of Atul Gawande, Siddhartha Mukherjee, and Abraham Verghese, The Cancer Chronicles is endlessly surprising and as radiant in its prose as it is authoritative in its eye-opening science.

A Cancer in the Family

Take Control of Your Genetic Inheritance

Author: Theodora Ross,Siddhartha Mukherjee

Publisher: Avery

ISBN: 1101982837

Category: BIOGRAPHY & AUTOBIOGRAPHY

Page: 288

View: 9161

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Using her own family's story (including her diagnosis with Inherited Melanoma), the latest science of cancer genetics and her experience as a practicing physician, Ross shows readers how to spot the patterns of inherited cancer, how to get tested for cancer-causing genes and what to do if you have one. A Cancer in the Family is the first authoritative, go-to text for people facing inherited cancer. It empowers readers to make decisions that will keep them and their families healthy.

The Secret History of the War on Cancer

Author: Devra Davis

Publisher: PublicAffairs

ISBN: 0465015689

Category: Health & Fitness

Page: 529

View: 2287

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An exposâe of the mishandling of the war on cancer looks at how the influence of industries making or using cancer-causing products affects government policy, laws, and research regarding the causes, prevention, and treatment of cancers.

Surviving American Medicine

Author: Cary Presant

Publisher: iUniverse

ISBN: 147593775X

Category: Health & Fitness

Page: 304

View: 7408

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We live in a time when the business of health-care has superseded the care of health. Health-care reform is a reality happening every day - and for you it means new ways of getting your care.

Superbug

The Fatal Menace of MRSA

Author: Maryn McKenna

Publisher: Simon and Schuster

ISBN: 9781439171837

Category: Medical

Page: 288

View: 5639

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LURKING in our homes, hospitals, schools, and farms is a terrifying pathogen that is evolving faster than the medical community can track it or drug developers can create antibiotics to quell it. That pathogen is MRSA—methicillin-resistant Staphyloccocus aureus—and Superbug is the first book to tell the story of its shocking spread and the alarming danger it poses to us all. Doctors long thought that MRSA was confined to hospitals and clinics, infecting almost exclusively those who were either already ill or old. But through remarkable reporting, including hundreds of interviews with the leading researchers and doctors tracking the deadly bacterium, acclaimed science journalist Maryn McKenna reveals the hidden history of MRSA’s relentless advance—how it has overwhelmed hospitals, assaulted families, and infiltrated agriculture and livestock, moving inexorably into the food chain. Taking readers into the medical centers where frustrated physicians must discard drug after drug as they struggle to keep patients alive, she discloses an explosion of cases that demonstrate how MRSA is growing more virulent, while evolving resistance to antibiotics with astonishing speed. It may infect us at any time, no matter how healthy we are; it is carried by a stunning number of our household pets; and it has been detected in food animals from cows to chickens to pigs. With the sensitivity of a novelist, McKenna portrays the emotional and financial devastation endured by MRSA’s victims, vividly describing the many stealthy ways in which the pathogen overtakes the body and the shock and grief of parents whose healthy children were felled by infection in just hours. Through dogged detective work, she discloses the unheard warnings that predicted the current crisis and lays bare the flaws that have allowed MRSA to rage out of control: misplaced government spending, inadequate public health surveillance, misguided agricultural practices, and vast overuse of the few precious drugs we have left. Empowering readers with the knowledge they need for self-defense, Superbug sounds an alarm: MRSA has evolved into a global emergency that touches almost every aspect of modern life. It is, as one deeply concerned researcher tells McKenna, "the biggest thing since AIDS."

How Cancer Works

Author: Lauren Sompayrac

Publisher: Jones & Bartlett Learning

ISBN: 9780763718213

Category: Family & Relationships

Page: 110

View: 3583

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Lauren Sompayrac explains the basics of cancer: what it is, what it does, and what is being done to try to cure it.

Cancer Ward

Author: Aleksandr Solzhenitsyn

Publisher: Random House

ISBN: 1448114462

Category: Fiction

Page: 576

View: 7396

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FROM THE NOBEL PRIZE-WINNING AUTHOR OF THE GULAG ARCHIPELAGO, ALEKSANDR SOLZHENITSYN ‘Solzhenitsyn is one of the towering figures of the age, as a writer, as moralist, as hero’ Edward Crankshaw After years in enforced exile on the Kazakhstan steppes, a cancer diagnosis brings Oleg Kostoglotov to Ward 13. Brutally treated in squalid conditions, and faced with ward staff and other patients from across the Soviet Union, Kostoglotov finds himself thrown once again into the gruelling mechanics of a state still haunted by Stalinism. One of the great allegorical masterpieces of world literature, Cancer Ward is both a deeply compassionate study of people facing terminal illness and a brilliant dissection of the “cancerous” Soviet police state. Withdrawn from publication in Russia in 1964, it became, along with One Day in the Life of Ivan Denisovich, a work that awoke the conscience of the world.

Toms River

A Story of Science and Salvation

Author: Dan Fagin

Publisher: Bantam

ISBN: 055380653X

Category: Biography & Autobiography

Page: 538

View: 6978

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A Newsday investigative reporter presents a narrative account of the 1971 industrial waste dumping incident in Toms River, New Jersey, that led to a cluster of childhood cancers and culminated in decades of legal fights, a record settlement and an unprecedented government study linking pollution to illness. 15,000 first printing.

Swimming in a Sea of Death

A Son's Memoir

Author: David Rieff

Publisher: Simon and Schuster

ISBN: 1416554289

Category: Biography & Autobiography

Page: 364

View: 915

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Both a memoir and an investigation, Swimming in a Sea of Death is David Rieff's loving tribute to his mother, the writer Susan Sontag, and her final battle with cancer. Rieff's brave, passionate, and unsparing witness of the last nine months of her life, from her initial diagnosis to her death, is both an intensely personal portrait of the relationship between a mother and a son, and a reflection on what it is like to try to help someone gravely ill in her fight to go on living and, when the time comes, to die with dignity. Rieff offers no easy answers. Instead, his intensely personal book is a meditation on what it means to confront death in our culture. In his most profound work, this brilliant writer confronts the blunt feelings of the survivor -- the guilt, the self-questioning, the sense of not having done enough. And he tries to understand what it means to desire so desperately, as his mother did to the end of her life, to try almost anything in order to go on living. Drawing on his mother's heroic struggle, paying tribute to her doctors' ingenuity and faithfulness, and determined to tell what happened to them all, Swimming in a Sea of Death subtly draws wider lessons that will be of value to others when they find themselves in the same situation.

The Death of Cancer

After Fifty Years on the Front Lines of Medicine, a Pioneering Oncologist Reveals Why the War on Cancer Is Winnable--and How We Can Get There

Author: Vincent T. DeVita, Jr., M.D.,Elizabeth DeVita-Raeburn

Publisher: Sarah Crichton Books

ISBN: 0374714177

Category: Medical

Page: 336

View: 9612

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Cancer touches everybody’s life in one way or another. But most of us know very little about how the disease works, why we treat it the way we do, and the personalities whose dedication got us where we are today. For fifty years, Dr. Vincent T. DeVita Jr. has been one of those key players: he has held just about every major position in the field, and he developed the first successful chemotherapy treatment for Hodgkin’s lymphoma, a breakthrough the American Society of Clinical Oncologists has called the top research advance in half a century of chemotherapy. As one of oncology’s leading figures, DeVita knows what cancer looks like from the lab bench and the bedside. The Death of Cancer is his illuminating and deeply personal look at the science and the history of one of the world’s most formidable diseases. In DeVita’s hands, even the most complex medical concepts are comprehensible. Cowritten with DeVita’s daughter, the science writer Elizabeth DeVita-Raeburn, The Death of Cancer is also a personal tale about the false starts and major breakthroughs, the strong-willed oncologists who clashed with conservative administrators (and one another), and the courageous patients whose willingness to test cutting-edge research helped those oncologists find potential treatments. An emotionally compelling and informative read, The Death of Cancer is also a call to arms. DeVita believes that we’re well on our way to curing cancer but that there are things we need to change in order to get there. Mortality rates are declining, but America’s cancer patients are still being shortchanged—by timid doctors, by misguided national agendas, by compromised bureaucracies, and by a lack of access to information about the strengths and weaknesses of the nation’s cancer centers. With historical depth and authenticity, DeVita reveals the true story of the fight against cancer. The Death of Cancer is an ambitious, vital book about a life-and-death subject that touches us all.

Principles of Clinical Cancer Genetics

A Handbook from the Massachusetts General Hospital

Author: Daniel C. Chung,Daniel A. Haber

Publisher: Springer Science & Business Media

ISBN: 9780387938462

Category: Medical

Page: 227

View: 687

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Advances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.

The Biology of Cancer, Second Edition

Author: Robert Weinberg

Publisher: Garland Science

ISBN: 1317963466

Category: Science

Page: 960

View: 4802

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Thoroughly updated and incorporating the most important advances in the fast-growing field of cancer biology, The Biology of Cancer, Second Edition, maintains all of its hallmark features admired by students, instructors, researchers, and clinicians around the world. The Biology of Cancer is a textbook for students studying the molecular and cellular bases of cancer at the undergraduate, graduate, and medical school levels. The principles of cancer biology are presented in an organized, cogent, and in-depth manner. The clarity of writing, supported by an extensive full-color art program and numerous pedagogical features, makes the book accessible and engaging. The information unfolds through the presentation of key experiments that give readers a sense of discovery and provide insights into the conceptual foundation underlying modern cancer biology.

One Renegade Cell

How Cancer Begins

Author: Robert A. Weinberg

Publisher: Basic Books

ISBN: 9780786724017

Category: Science

Page: 176

View: 4008

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Cancer research has reached a major turning point, and no one is better qualified to explain the past two deacades' dramatic leaps forward in understanding this disease than world-renowned molecular biologist Robert Weinberg, director of the Oncology Research Laboratory at the Whitehead Institute in Cambridge, Massachusetts. In One Renegade Cell, Weinberg presents a state-of-the-art account of how cancer begins and how, one day, it will be cured.