Research Methods in Biomineralization Science

Author: N.A

Publisher: Elsevier

ISBN: 0124166555

Category: Science

Page: 704

View: 5173

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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in biomineralization science, and includes sections on such topics as determining solution chemistry, structure and nucleation; probing structure and dynamics at surfaces; and interfaces mapping biomineral and morphology and ultrastructure. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Contains sections on such topics as and includes sections on such topics as determining solution chemistry, structure and nucleation; probing structure and dynamics at surfaces; and interfaces mapping biomineral and morphology and ultrastructure

Anwendungen

Von Urban Mining bis NanoGeoScience

Author: Michael Quednau

Publisher: Walter de Gruyter GmbH & Co KG

ISBN: 3110422875

Category: Science

Page: 408

View: 6873

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Von chemischen und mikrobiologischen Grundlagen bis zu Anwendungen im Bergbau und der industriellen Synthese von Nanopartikeln fasst dieses zweibändige Lehrbuch zum ersten Mal die Gesamtheit der Geomikrobiologie für den Studenten zusammen. Dieser zweite Teil befasst sich mit Methoden für industrielle Anwendungen, Urban Mining, der Skalierung, sowie speziellen Anwendungen.

Biomineralization and Biomaterials

Fundamentals and Applications

Author: Conrado Aparicio,Maria Pau Ginebra

Publisher: Woodhead Publishing

ISBN: 1782423567

Category: Technology & Engineering

Page: 482

View: 7042

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Biomineralization is a natural process by which living organisms form minerals in association with organic biostructures to form hybrid biological materials such as bone, enamel, dentine and nacre among others. Scientists have researched the fundamentals of these processes and the unique structures and properties of the resulting mineralized tissues. Inspired by them, new biomaterials for tissue engineering and regenerative medicine have been developed in recent years. Biomineralization and biomaterials: fundamentals and applications looks at the characteristics of these essential processes and natural materials and describes strategies and technologies to biomimetically design and produce biomaterials with improved biological performance. Provides a thorough overview of the biomineralization process Presents the most recent information on the natural process by which crystals in tissues form into inorganic structures such as bone, teeth, and other natural mineralized tissues Investigates methods for improving mineralization Explores new techniques that will help improve the biomimetic process

Protein Kinase Inhibitors in Research and Medicine

Author: N.A

Publisher: Academic Press

ISBN: 9780123984623

Category: Medical

Page: 252

View: 4603

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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers protein kinase inhibitors in research and medicine, and includes chapters on such topics as fragment-based screening, broad kinome profiling of kinase inhibitors, and designing drug-resistant kinase alleles. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Contains sections focusing on protein kinase inhibitors in research and medicine

Handbook of Crystal Growth

Fundamentals

Author: Tatau Nishinaga

Publisher: Elsevier

ISBN: 0444593764

Category: Science

Page: 1214

View: 1473

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Volume IA Handbook of Crystal Growth, 2nd Edition (Fundamentals: Thermodynamics and Kinetics) Volume IA addresses the present status of crystal growth science, and provides scientific tools for the following volumes: Volume II (Bulk Crystal Growth) and III (Thin Film Growth and Epitaxy). Volume IA highlights thermodynamics and kinetics. After historical introduction of the crystal growth, phase equilibria, defect thermodynamics, stoichiometry, and shape of crystal and structure of melt are described. Then, the most fundamental and basic aspects of crystal growth are presented, along with the theories of nucleation and growth kinetics. In addition, the simulations of crystal growth by Monte Carlo, ab initio-based approach and colloidal assembly are thoroughly investigated. Volume IB Handbook of Crystal Growth, 2nd Edition (Fundamentals: Transport and Stability) Volume IB discusses pattern formation, a typical problem in crystal growth. In addition, an introduction to morphological stability is given and the phase-field model is explained with comparison to experiments. The field of nanocrystal growth is rapidly expanding and here the growth from vapor is presented as an example. For the advancement of life science, the crystal growth of protein and other biological molecules is indispensable and biological crystallization in nature gives many hints for their crystal growth. Another subject discussed is pharmaceutical crystal growth. To understand the crystal growth, in situ observation is extremely powerful. The observation techniques are demonstrated. Volume IA Explores phase equilibria, defect thermodynamics of Si, stoichiometry of oxides and atomistic structure of melt and alloys Explains basic ideas to understand crystal growth, equilibrium shape of crystal, rough-smooth transition of step and surface, nucleation and growth mechanisms Focuses on simulation of crystal growth by classical Monte Carlo, ab-initio based quantum mechanical approach, kinetic Monte Carlo and phase field model. Controlled colloidal assembly is presented as an experimental model for crystal growth. Volume IIB Describes morphological stability theory and phase-field model and comparison to experiments of dendritic growth Presents nanocrystal growth in vapor as well as protein crystal growth and biological crystallization Interprets mass production of pharmaceutical crystals to be understood as ordinary crystal growth and explains crystallization of chiral molecules Demonstrates in situ observation of crystal growth in vapor, solution and melt on the ground and in space

Nanoscience and Nanotechnology for Human Health

Author: Bert Müller,Marcel Van de Voorde

Publisher: John Wiley & Sons

ISBN: 3527692045

Category: Technology & Engineering

Page: 410

View: 2157

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Unique in combining the expertise of practitioners from university hospitals and that of academic researchers, this timely monograph presents selected topics catering specifically to the needs and interests of natural scientists and engineers as well as physicians who are concerned with developing nanotechnology-based treatments to improve human health. To this end, the book cover the materials aspects of nanomedicine, such as the hierarchical structure of biological materials, the imaging of hard and soft tissues and, in particular, concrete examples of nanotechnology-based approaches in modern medical treatments. The whole is rounded off by a discussion of the opportunities and risks of using nanotechnology and nanomaterials in medicine, backed by case studies taken from real life.

Circadian Rhythms and Biological Clocks

Author: N.A

Publisher: Academic Press

ISBN: 0128013419

Category: Science

Page: 488

View: 5347

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Two new volumes of Methods in Enzymology continue the legacy of this premier serial with quality chapters authored by leaders in the field. Circadian Rhythms and Biological Clocks Part A and Part B is an exceptional resource for anybody interested in the general area of circadian rhythms. As key elements of timekeeping are conserved in organisms across the phylogenetic tree, and our understanding of circadian biology has benefited tremendously from work done in many species, the volume provides a wide range of assays for different biological systems. Protocols are provided to assess clock function, entrainment of the clock to stimuli such as light and food, and output rhythms of behavior and physiology. This volume also delves into the impact of circadian disruption on human health. Contributions are from leaders in the field who have made major discoveries using the methods presented here. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Keeping with the interdisciplinary nature of the circadian rhythm field, the volume includes diverse approaches towards the study of rhythms, from assays of biochemical reactions in unicellular organisms to monitoring of behavior in humans.

Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism

Author: N.A

Publisher: Elsevier

ISBN: 0124166571

Category: Science

Page: 536

View: 3364

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Volume 542 of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This new volume covers research methods providing a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as "yet another" general hallmark of cancer, accumulating evidence suggests that the metabolic alterations of each neoplasm rather represent a molecular signature that intimately accompanies, and hence cannot be severed from, all facets of malignant transformation. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Provides theoretical overview on metabolic alterations of cancer cells, and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo

Cell-wide Metabolic Alterations Associated with Malignancy

Author: N.A

Publisher: Academic Press

ISBN: 0128014830

Category: Medical

Page: 384

View: 9272

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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods providing a a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as "yet another" general hallmark of cancer, accumulating evidence suggests that the metabolic alterations of each neoplasm rather represent a molecular signature that intimately accompanies, and hence cannot be severed from, all facets of malignant transformation. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Contains sections on such topics providing a a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo.

Regulated Cell Death Part A

Apoptotic Mechanisms

Author: Avi Ashkenazi,Junying Yuan,Jim Wells

Publisher: Elsevier

ISBN: 0124171753

Category: Science

Page: 504

View: 4649

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Regulated Cell Death Part A & Part B of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Regulated Cell Death Part A & Part B contains sections on such topics as apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches

The Use of CRISPR/cas9, ZFNs, TALENs in Generating Site-Specific Genome Alterations

Author: N.A

Publisher: Academic Press

ISBN: 0128013346

Category: Science

Page: 570

View: 8925

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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers recent research and methods development for changing the DNA sequence within the genomes of cells and organisms. Focusing on enzymes that generate double-strand breaks in DNA, the chapters describe use of molecular tools to introduce or delete genetic information at specific sites in the genomes of animal, plant and bacterial cells. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Contains sections on such topics as genome editing, genome engineering, CRISPR, Cas9, TALEN and zinc finger nuclease

Mitochondrial Function

Author: Anne N. Murphy,David C. Chan

Publisher: Academic Press

ISBN: 9780128014158

Category: Medical

Page: 506

View: 5094

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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. Methods to assess mitochondrial function is of great interest to neuroscientists studying chronic forms of neurodegeneration, including Parkinson's, Alzheimer's, ALS, Huntington's and other triplet repeat diseases, but also to those working on acute conditions such as stroke and traumatic brain injury. This volume covers research methods on how to assess the life cycle of mitochondria including trafficking, fusion, fission, and degradation. Multiple perspectives on the complex and difficult problem of measurement of mitochondrial reactive oxygen species production with fluorescent indicators and techniques ranging in scope from measurements on isolated mitochondria to non-invasive imaging of metabolic function. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Provides invaluable details on state-of-the-art methods to assess a broad array of mitochondrial functions

Regulated Cell Death Part B

Necroptotic, Autophagic and other Non-apoptotic Mechanisms

Author: N.A

Publisher: Academic Press

ISBN: 0128016191

Category: Science

Page: 352

View: 3194

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Regulated Cell Death Part A & Part B of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Regulated Cell Death Part A & Part B contains sections on such topics as apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches

Issues in General Science and Scientific Theory and Method: 2013 Edition

Author: N.A

Publisher: ScholarlyEditions

ISBN: 1490109536

Category: Science

Page: 1201

View: 2461

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Issues in General Science and Scientific Theory and Method: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Mixed Methods Research. The editors have built Issues in General Science and Scientific Theory and Method: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Mixed Methods Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in General Science and Scientific Theory and Method: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Biomineralization

Progress in Biology, Molecular Biology and Application

Author: Edmund Bäuerlein

Publisher: John Wiley & Sons

ISBN: 3527604618

Category: Science

Page: 361

View: 7047

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Now over 50 % new contents. Incorporating the surprisingly rapid advances in this field since the publication of the successful first edition, this intensively updated and expanded new edition covers all the background as well as the latest results. Now organized according to the main biominerals, the book reflects the increasingly important biochemical aspects and medicinal applications, with four new chapters on biomineralization in mammals, including humans. The whole is rounded off with an entire chapter dedicated to modern methods, especially physical ones that have advanced the field over the last five years. The international team of renowned authors, under the direction of a leading expert in the field, provide first-hand research results from their own relevant fields. The result is an interdisciplinary must-have account, designed for a broad community of researchers.

Issues in General Science and Scientific Theory and Method: 2011 Edition

Author: N.A

Publisher: ScholarlyEditions

ISBN: 1464963479

Category: Science

Page: 3278

View: 720

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Issues in General Science and Scientific Theory and Method: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about General Science and Scientific Theory and Method. The editors have built Issues in General Science and Scientific Theory and Method: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about General Science and Scientific Theory and Method in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in General Science and Scientific Theory and Method: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Magnetite Biomineralization and Magnetoreception in Organisms

A New Biomagnetism

Author: Joseph L. Kirschvink,Douglas S. Jones,Bruce J. MacFadden

Publisher: Springer Science & Business Media

ISBN: 1461303133

Category: Science

Page: 704

View: 443

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The mystery of how migrating animals find their way over unfamiliar terrain has intrigued people for centuries, and has been the focus of productive research in the biological sci ences for several decades. Whether or not the earth's magnetic field had anything to do with their navigational abilities has sufaced and been dismissed several times, beginning at least in the mid to late 1800s. This topic generally remained out of the mainstream of scientific research for two reasons: (1) The apparent irreproducibility of many of the be havioral experiments which were supposed to demonstrate the existence of the magnetic sense; and (2) Perceived theoretical difficulties which were encountered when biophysi cists tried to understand how such a sensory system might operate. However, during the mid to late 1960s as the science of ethology (animal behavior) grew, it became clear from studies on bees and birds that the geomagnetic field is used under a variety of conditions. As more and more organisms were found to have similar abilities, the problem shifted back to the question as to the basis of this perception. Of the various schemes for trans ducing the geomagnetic field to the nervous system which have been proposed, the hy pothesis of magnetite-based magnetoreception discussed at length in this volume has per haps the best potential for explaining a wide range of these effects, even though this link is as yet clear only in the case of magnetotactic bacteria.

Advances in Bioartificial Materials and Tissue Engineering Research and Application: 2011 Edition

Author: N.A

Publisher: ScholarlyEditions

ISBN: 1464921261

Category: Technology & Engineering

Page: 608

View: 9637

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Advances in Bioartificial Materials and Tissue Engineering Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Bioartificial Materials and Tissue Engineering. The editors have built Advances in Bioartificial Materials and Tissue Engineering Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bioartificial Materials and Tissue Engineering in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Bioartificial Materials and Tissue Engineering Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Intracellular biomineralization in bacteria

Author: Damien Faivre

Publisher: Frontiers E-books

ISBN: 2889192725

Category:

Page: N.A

View: 1248

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Bacteria can sequester metals and other ions intracellularly in various forms ranging from poorly ordered deposits to well- ordered mineral crystals. Magnetotactic bacteria provide one example of such intracellular deposits. They synthesize intracellular magnetic minerals of magnetite (Fe3O4) and/or greigite (Fe3S4) magnetosomes which are generally less than 150 nm and organized into one or multiple chain structures. The magnetosome chain(s) act like a compass needle to facilitate the navigation of magnetotactic bacteria by using the Earth’s magnetic field. Due to their ubiquitous distribution in aquatic and sedimentary environments, magnetotactic bacteria play important roles in global iron cycling. Other intracellular mineral phases have been evidenced in bacteria such as As2S3, CaCO3, CdS, Se(0) or various metal phosphates which may play as well a significant role in the geochemical cycle of these elements. However, in contrast to magnetotactic bacteria, the biological and environmental function of these particles remains a matter of debate. In recent years, such intracellularly biomineralizaing bacteria have become an attractive model system for investigating the molecular mechanisms of organelle-like structure formation in prokaryotic cells. The geological significance of intracellular biomineralization is important; spectacular examples are fossil magnetosomes that may significantly contribute to the bulk magnetization of sediments and act as potential archives of paleoenvironmental changes. In addition, intracellular mineral deposits formed by bacteria have potentially versatile applications in biotechnological and biomedical fields. After more than four decades of research, the knowledge on intracellularly biomineralizing bacteria has greatly improved. The aim of this Research Topic is to highlight recent advances in our understanding of intracellular biomineralization by bacteria. Magnetotactic bacteria are a system of choice for that topic but other intracellularly biomineralizing bacteria may bring a unique perspective on that process. Research papers, reviews, perspectives, and opinion papers on (i) the diversity and ecology of intracellularly biomineralizing bacteria, (ii) the molecular mechanisms of intracellular biomineralization, (iii) the chemo- and magneto-taxis behaviors of magnetotactic bacteria, (iv) the involvement of intracellularly biomineralizing bacteria in local or global biogeochemical cycling, (v) the paleoenvironmental reconstructions and paleomagnetic signals based on fossil magnetosomes, (vi) and the applications of intracellular minerals in biomaterial and biotechnology were welcomed.