Author: Patrick Ness

Publisher: HarperTeen

ISBN: 9781406378696

Category: Fiction

Page: 286

View: 9472


Synopsis coming soon.......

Modified-Release Drug Delivery Technology

Author: Michael J. Rathbone,Jonathan Hadgraft,Michael S. Roberts

Publisher: CRC Press

ISBN: 0824708695

Category: Medical

Page: 1032

View: 1790


Describing formulation challenges and their solutions in the design, development, and commercialization of modified-release drugs delivery systems, this book contains eighty papers that review recent developments in design and manufacturing techniques. It includes detailed descriptions of extended release drug products for the oral, nasal, ophthalmic, pulmonary, vaginal, dermal and transdermal pathways. With the exception of the final section addressing regulatory issues, each section covers a particular route for drug delivery and opens with an overview of the anatomical, physiological, and pharmaceutical basics of each route before moving on to cover specific technologies.

Dendritic Neurotransmitter Release

Author: Mike Ludwig

Publisher: Springer Science & Business Media

ISBN: 0387236961

Category: Medical

Page: 333

View: 7025


The transmission of the nervous impulse is always from the dendritic branches and the cell body to the axon or functional process. Every neuron, then, possesses a receptor apparatus, the body and the dendritic prolongations, an apparatus of emission, the axon, and the apparatus of distribution, the terminal arborization of the nerve fibers. I designated the foregoing principle: the theory of dynamic polarization (Cajal 1923). Ever since the beautiful drawings from Golgi and Cajal, we have been familiar with the organisation of neurones into dendritic, somatic and axonal compartments. Cajal proposed that these cellular compartments were specialised, resulting in his concept of ^dynamic polarisation'. He considered dendrites to be passive elements that simply transferred information from inputs to the soma. Since the discovery that dendrites of many neural populations release neuroactive substances and in doing so, alter neuronal output, it is now apparent that this theory requires qualification. This book presents recent developments in the neurophysiology of dendritic release of several chemical classes of transmitters in a number of different areas of the mammalian central nervous system. Once released from a neuron, these substances can act as neurotransmitters and/or neuromodulators, to autoregulate the original neuron, its synaptic inputs, and adjacent cells or, by volume transmission, to affect distant cells. In some systems, dendritic transmitter release is part independent of secretion from axon terminal signifying a selective control of the dendritic compartment.

Oral Controlled Release Formulation Design and Drug Delivery

Theory to Practice

Author: Hong Wen,Kinam Park

Publisher: John Wiley & Sons

ISBN: 9781118060322

Category: Science

Page: 376

View: 6484


This book describes the theories, applications, and challenges for different oral controlled release formulations. This book differs from most in its focus on oral controlled release formulation design and process development. It also covers the related areas like preformulation, biopharmaceutics, in vitro-in vivo correlations (IVIVC), quality by design (QbD), and regulatory issues.

Language and Release

Sarvajñātman's Pañcaprakriyā

Author: Ivan Kocmarek

Publisher: Motilal Banarsidass Publ.

ISBN: 9788120800045

Category: Philosophy

Page: 147

View: 8892


We find here a translation for the first time of the sanskrit philosophical work entitled Pancaprakriya which belongs to the relatively early Advaita Vedanta thinker Sarvajnatman and a thematic analysis of the contents of that work. The Pancaprakriya is a menual of Advaita Vedanta philosophy of language which for Sarcajnatman is reduced to the discernment of the proper meaning of certain great Upanisadic statements or mahavakyss such as Iam Brahman and That thou art. Through the approprition of such a proper understanding which resorts to the secondary of implied usafe of language the qualifies striver after enlghtenment obtains release from bondage int he world.

Who to Release?

Parole, Fairness and Criminal Justice

Author: Nicola Padfield

Publisher: Taylor & Francis

ISBN: 1843922274

Category: Social Science

Page: 262

View: 9032


This book is about the decision-making processes which result in the release of serious offenders back into 'the community'. It has become an increasingly high-profile issue amongst both public and the media, and raises a number of important concerns and questions. Are too many offenders being released, or is it a question of inadequate supervision on release? Or should we learn to live with the uncomfortable fact that some offenders will unpredictably re-offend? At the same time, the number of ex-prisoners in the community who are recalled to prison, very often simply because they are causing their supervisors significant concern and not because they have re-offended, is at a record high. Are those responsible for recall in fact being too cautious? Is the Parole Board unduly cautious? Or do many of the problems lie not with individual decision-makers but with the 'system'? This book addresses these questions, and explores the changing role of the Parole Board across the range of its responsibilities, including the prediction of risk and deciding on the release (or continued detention) of the growing number of recalled prisoners and of those subject to indeterminate sentences. In doing so it aims to rectify the lack of attention given-by lawyers, academics and practitioners to ''back door sentencing' (where the real length of a sentence is decided by those who take the decision to release) compared to 'front door sentencing' (decisions taken by judges or magistrates in court). Particular attention is given to the important changes to the early release scheme, and therefore to the role and functions of the Parole Board, in the Criminal Justice Act 2003. The contributors approach the subject from a wide range of perspectives-as academics, practitioners, lawyers and psychologists amongst others.

Handbook of Antiblocking, Release, and Slip Additives

Author: George Wypych

Publisher: ChemTec Publishing

ISBN: 1895198313

Category: Technology & Engineering

Page: 327

View: 4691


The Handbook of Antiblocking, Release, and Slip Additives is the first ever book written on this subject. These chemicals are of high industrial importance because of their widespread applications in industrial and consumer products. It is very important source of information for professionals in industry, research, academia, and government. Eighteen chemical families form the core of a large number of commercial products used by industry as antiblocking, release, and slip additives. These additives are used in the production of materials from 44 generic families of polymers. Polymers containing antiblocking, release, and slip additives are processed by 17 groups of processing methods. The processing methods are used by at least 25 industries. A complete, up-to-date analysis of the literature and patents available on these additives is included in the book. The book considers all essential aspects of chemistry, physical properties, influence on properties of final products, formulations, methods of incorporation, analysis, and effects on health and environment.

Neurotransmitter Release and Its Modulation

Biochemical Mechanisms, Physiological Function and Clinical Relevance

Author: David A. Powis,Stephen J. Bunn

Publisher: Cambridge University Press

ISBN: 9780521446167

Category: Medical

Page: 356

View: 2196


A uniquely comprehensive and integrated account of neurotransmitter modulation. Suitable for neuroscientists and non-specialists alike.

Pretrial Release of Felony Defendants in State Courts

State Court Processing Statistics, 1990-2004

Author: Thomas H. Cohen

Publisher: DIANE Publishing

ISBN: 1437932606


Page: 18

View: 9978


Between 1990 and 2004, 62% of felony defendants in State courts in the 75 largest counties were released prior to the disposition of their case. Beginning in 1998, financial pretrial releases, requiring the posting of bail, were more prevalent than non-financial releases. This increase in the use of financial releases was mostly the result of a decrease in the use of release on recognizance (ROR), coupled with an increase in the use of commercial surety bonds. Compared to ROR, defendants on financial release were more likely to make all scheduled court appearances. Defendants released on an unsecured bond or as part of an emergency release were most likely to have a bench warrant issued because they failed to appear in court. Tables.

Release the Sun

Author: William Sears

Publisher: Baha'i Publishing Trust

ISBN: 9781931847094

Category: Biography & Autobiography

Page: 323

View: 2605


Cover subtitle: the story of the Bab, the prophet-herald of the Bahai faith, and the extraordinary time in which he lived.

The Release 12 Primer - Shining a Light on the Release 12 World

Author: Barbara Matthews,John Stouffer,Karen Brownfield


ISBN: 0615238440

Category: Computers

Page: 256

View: 5566


If you've been thinking about installing or upgrading to Release 12 but need to understand more about why you should do so, this is the book for you. For functional users, The Release 12 Primer highlights the modules that have changed the most. Read about Oracle's Global Business Release, Master Data Management, MOAC and the Swan Interface. Then see how it all comes together for the Financials and Procurement product families, Supply Chain Management, CRM, and Projects. And if you've always wanted to understand more about the underlying technology, but found all the terminology too complex to sort through, this book covers the technical architecture, security issues, and even Fusion, targeting both functional and technical readers. "The Release 12 Primer provides the real story on the latest version of the Oracle E-Business Suite and its technical underpinnings. If you only buy one book on Oracle E-Business Release 12, buy this one." - Floyd M. Teter, Systems Engineer, JPL

Air Release, Air/Vacuum Valves and Combination Air Valves (M51)

Author: AWWA Staff

Publisher: American Water Works Association

ISBN: 1613001819

Category: Technology & Engineering

Page: 37

View: 9314


The American Water Works Association had this guide written to assist those who will choose, locate and/or install air valves for water use (it doesn't contain the AWWA standard, which is a separate publication). The use and principles of air valves are discussed in an introduction, the remainder of

Soft Tissue Release

Author: Jane Johnson

Publisher: Human Kinetics

ISBN: 073607712X

Category: Medical

Page: 163

View: 9083


Soft Tissue Release is a clear, concise, and practical book that guides you in understanding and applying the three types of soft tissue release (STR): passive (clients do not help), active assisted (clients and therapists work together), and active (clients do it on their own). Rather than focus on the specific purposes of soft tissue release, this text provides basic information about the therapy and prepares readers to perform the techniques. The result is a text that professionals and students in massage therapy, physiotherapy, and osteopathy will find invaluable. Soft Tissue Releasethoroughly explains the differences between the three types of STR by providing step-by-step descriptions on performing each type along with the key holds, moves, and stances for various muscles. The descriptions are accompanied by handy reference charts indicating the types of clients and situations in which each technique is particularly useful. Complete instructions explain how to apply STR to various parts of the body—the trunk, the lower limbs, and the upper limbs—and detail the advantages and disadvantages of each technique. Numerous full-color photos depict the locks and stretches. The book also explains how to use alternative options—such as massage tools and forearms, fists, and elbows—to protect the hands and thumbs from overuse. Tips sidebars provide short, practical comments on applying the techniques, while Client Talk boxes share the author's experiences and provide insight on situations that a therapist is likely to encounter. Each chapter ends with Quick Questions to test knowledge of the information, and answers are provided at the end of the book. A quick-reference photo index allows readers to look up techniques based on the client's position—prone, supine, sitting, or side lying—and find the page number for the complete instructions for that technique. Finally, Soft Tissue Release shows how to incorporate the proper techniques into a treatment program. The book guides readers through the consultation process and provides examples of initial questions to ask clients and various assessment forms that therapists can use in identifying clients' needs. Using case studies and comparisons, the book shows how the data gleaned from clients can guide the design of an effective treatment program. Soft Tissue Releasewill help the STR techniques come alive through its clear, detailed instruction and the numerous photos showing the techniques being applied by professionals. Whether you are a student or a professional, Soft Tissue Release will help you gain proficiency and confidence in these techniques.

The Release of Nelson Mandela

Author: John Malam

Publisher: Cherrytree Books

ISBN: 1842345370

Category: South Africa

Page: 32

View: 895


The 'Dates with History' series explores noted events of the past, describing what happened on each particular day and setting it in its wider historical context.

Controlled-Release Delivery Systems for Pesticides

Author: Herbert B. Scher

Publisher: CRC Press

ISBN: 9780824719883

Category: Science

Page: 336

View: 3565


Highlighting means of reducing toxicity, increasing efficacy, lessening environmental impact, and facilitating product development, this work covers up-to-date advances in pesticide delivery technologies. It evaluates pesticide formulations and their use in mixtures that reduce physical incompatibilities in spray tanks and biological anatagonism in the field.