Microbial-based Polyhydroxyalkanoates

Author: Amirul Al-Ashraf Abdullah

Publisher: Smithers Rapra

ISBN: 1909030643

Category: Science

Page: 190

View: 5031

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Polyhydroxyalkanoate (PHA) is a group of natural biopolymers synthesised by a wide variety of microbial genera. It is a biodegradable and biocompatible thermoplastic consisting of a repeated chain of various hydroxyalkanoate monomers.PHA is envisioned to be one of the most prospective and futuristic materials which is beneficial to mankind and to the world. In current world trends which concerns at the sustainable development from renewable and eco-friendly resources, PHA has garnered a growing attention as an alternative to petroleum based plastics.The book comes with two main objectives. In this book, major pipelines in processing this beneficial biopolymer were first reviewed from upstream to the downstream. The upstream processing includes the isolation of PHA producers, biosynthesis of PHA, genetic modification of PHA producers and optimisation of PHA production; meanwhile the downstream processing covers the PHA recovery and purification, degradation, quantification, characterisation, as well as the application of PHA. Readers will be exposed to the introductory information, along with some necessary concepts behind each subject.The second objective of this book is to provide readers with the recent advances on each PHA processing field. Being updated with the recent findings, this will provide an insight to readers on how the research trends for each subject are evolving from time to time. These updates will become useful case studies and quick references to readers from various areas, either from academia or industry.

Recent Advances in Biotechnology Volume, 1: Microbial Biopolyester Production, Performance and Processing Microbiology, Feedstocks, and Metabolism

Author: Martin Koller

Publisher: Bentham Science Publishers

ISBN: 1681083256

Category: Science

Page: 500

View: 8377

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Global plastic production is estimated to be over 300Mt annually. Most conventional plastics are predominantly produced from fossil fuels and are highly resistant to biodegradation, and only a small share of about 20% of spent plastics is believed to be recycled, which is a cause for environmental concern. Biodegradable plastics would solve this concern as they are a sustainable alternative, yet these do not even cover 5% of the global plastic market. Microbial polyhydroxyalkanoates (PHAs) are a versatile group of polyesters produced by nature as prokaryotic storage materials. PHAs can be produced through sustainable bioprocess engineering and have displayed remarkable flexibility in their physical and chemical properties. PHAs are the subject of several scientific papers and numerous PHA patents have also been filed, generating significant interest in the plastic production industry. To develop overall sustainable and efficient production processes, all bioprocess steps need to be thoroughly understood and accounted for. These processes start with the selection of suitable inexpensive raw materials (microbes and enzymes), optimizing the process engineering and process regime, and conclude with the enhancement of product recovery in terms of time, energy, and material input. Microbial Biopolyester Production, Performance and Processing: Microbiology, Feedstocks, and Metabolism encompasses eight chapters that cover aspects of the microbiology and biotechnology of producing biodegradable plastics. The contents focus on the selection of powerful archaeal and eubacterial production strains, genetic engineering as a tool for optimized PHA production and inexpensive carbon sources for microbial cultures. The volume is a useful resource for bioprocess engineers, microbiologists, biotechnologists and chemical engineers interested in the basics of biodegradable plastic production. Recent Advances in Biotechnology is a book series comprising of peer-reviewed reference works and monographs that compile the latest developments in the field of biotechnology. Each volume has a thematic focus and features topical reviews written by experts. The series will highlight multidisciplinary perspectives to interested readers (biotechnologists, microbiologists, bioprocess engineers, agronomists, medical professionals, sustainability researchers etc.)

Recent Advances in Biotechnology Volume, 2: Microbial Biopolyester Production, Performance and Processing Bioengineering, Characterization, and Sustainability

Author: Martin Koller

Publisher: Bentham Science Publishers

ISBN: 1681083736

Category: Science

Page: 520

View: 1402

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Global plastic production is estimated to be over 300Mt annually. Most conventional plastics are predominantly produced from fossil fuels and are highly resistant to biodegradation, and only a small share of about 20% of spent plastics is believed to be recycled, which is a cause for environmental concern. Biodegradable plastics would solve this concern as they are a sustainable alternative, yet these do not even cover 5% of the global plastic market. Microbial polyhydroxyalkanoates (PHAs) are a versatile group of polyesters produced by nature as prokaryotic storage materials. PHAs can be produced through sustainable bioprocess engineering and have displayed remarkable flexibility in their physical and chemical properties. PHAs are the subject of several scientific papers and numerous PHA patents have also been filed, generating significant interest in the plastic production industry. To develop overall sustainable and efficient production processes, all bioprocess steps need to be thoroughly understood and accounted for. These processes start with the selection of suitable inexpensive raw materials (microbes and enzymes), optimizing the process engineering and process regime, and conclude with the enhancement of product recovery in terms of time, energy, and material input. Microbial Biopolyester Production, Performance and Processing: Bioengineering, Characterization, and Sustainability is a compilation of eight chapters covering bacterial polyesters, green plastics and PHAs from various angles. The contents of this volume focus on sustainable practices focus on the sustainability of processes that involve the synthesis and recycling of these meterials. The volume is a useful resource for bioprocess engineers, microbiologists, biotechnologists and chemical engineers interested in the basics of biodegradable plastic production.

Plastics from Bacteria

Natural Functions and Applications

Author: George Guo-Qiang Chen

Publisher: Springer Science & Business Media

ISBN: 9783642032875

Category: Science

Page: 450

View: 3283

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Due to the possibility that petroleum supplies will be exhausted in the next decades to come, more and more attention has been paid to the production of bacterial pl- tics including polyhydroxyalkanoates (PHA), polylactic acid (PLA), poly(butylene succinate) (PBS), biopolyethylene (PE), poly(trimethylene terephthalate) (PTT), and poly(p-phenylene) (PPP). These are well-studied polymers containing at least one monomer synthesized via bacterial transformation. Among them, PHA, PLA and PBS are well known for their biodegradability, whereas PE, PTT and PPP are probably less biodegradable or are less studied in terms of their biodegradability. Over the past years, their properties and appli- tions have been studied in detail and products have been developed. Physical and chemical modifications to reduce their cost or to improve their properties have been conducted. PHA is the only biopolyester family completely synthesized by biological means. They have been investigated by microbiologists, molecular biologists, b- chemists, chemical engineers, chemists, polymer experts, and medical researchers for many years. PHA applications as bioplastics, fine chemicals, implant biomate- als, medicines, and biofuels have been developed. Companies have been est- lished for or involved in PHA related R&D as well as large scale production. It has become clear that PHA and its related technologies form an industrial value chain in fermentation, materials, feeds, and energy to medical fields.

Bioprocessing for Value-Added Products from Renewable Resources

New Technologies and Applications

Author: Shang-Tian Yang

Publisher: Elsevier

ISBN: 9780080466712

Category: Technology & Engineering

Page: 684

View: 9448

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Bioprocessing for Value-Added Products from Renewable Resources provides a timely review of new and unconventional techniques for manufacturing high-value products based on simple biological material. The book discusses the principles underpinning modern industrial biotechnology and describes a unique collection of novel bioprocesses for a sustainable future. This book begins in a very structured way. It first looks at the modern technologies that form the basis for creating a bio-based industry before describing the various organisms that are suitable for bioprocessing - from bacteria to algae - as well as their unique characteristics. This is followed by a discussion of novel, experimental bioprocesses, such as the production of medicinal chemicals, the production of chiral compounds and the design of biofuel cells. The book concludes with examples where biological, renewable resources become an important feedstock for large-scale industrial production. This book is suitable for researchers, practitioners, students, and consultants in the bioprocess and biotechnology fields, and for others who are interested in biotechnology, engineering, industrial microbiology and chemical engineering. ·Reviews the principles underpinning modern industrial biotechnology ·Provides a unique collection of novel bioprocesses for a sustainable future ·Gives examples of economical use of renewable resources as feedstocks ·Suitable for both non-experts and experts in the bioproduct industry

Microbial Biomass Process Technologies and Management

Author: Basanta Kumara Behera,Ajit Varma

Publisher: Springer

ISBN: 3319539132

Category: Medical

Page: 306

View: 3709

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This book describes how microbes can be used as effective and sustainable resources to meet the current challenge of finding suitable and economical solutions for biopharmaceuticals, enzymes, food additives, nutraceuticals, value added biochemicals and microbial fuels, and discusses various aspects of microbial regulatory activity and its applications. It particularly focuses on the design, layout and other relevant issues in industrial microbe applications. Moreover, it discusses the entire microbial-product supply chain, from manufacturing sites to end users, both in domestic and international markets, providing insights into the global marketing of microbes and microbial biomass-derived products. Further, it includes topics concerning the effective production and utilization of eco-friendly biotechnology industries. It offers a valuable, ready-to-use guide for technologists and policymakers developing new biotechnologies.

Environmental Microbiology for Engineers, Second Edition

Author: Volodymyr Ivanov

Publisher: CRC Press

ISBN: 1498702155

Category: Science

Page: 413

View: 841

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Updated Edition Includes a New Chapter and Enhanced Study Material The second edition of Environmental Microbiology for Engineers explores the role that microorganisms play in the engineered protection and enhancement of an environment. Offering a perfect balance of microbiological knowledge and environmental biotechnology principles, it provides a practical understanding of microorganisms and their functions in the environment and in the environmental engineering systems. The book also presents a quantitative description of applied microbiological processes and their engineering design. This updated edition adds a new chapter on construction biotechnology, as well as a new quiz, tutorial banks, and exam questions with solutions to aid readers with performing the design calculations needed and to enhance understanding of the material. The book covers essential topics that include: Diversity and functions of microorganisms in environmental engineering systems Environmental bioengineering processes Applied microbial genetics and molecular biology Microbiology of water and wastewater treatment Biotreatment of solid waste and soil bioremediation Microbial monitoring of environmental engineering systems Biocorrosion and biodeterioration of materials Biocementation and bioclogging of soil Biopollution of indoor environment Biofouling of facilities, and more Environmental Microbiology for Engineers provides a practical understanding of microorganisms in the civil engineering process and their functions in the environmental engineering systems, and is designed for practicing environmental engineers working in the areas of wastewater, solid waste treatment, soil remediation and ground improvement.

Biopharmaceutical Processing

Development, Design, and Implementation of Manufacturing Processes

Author: Gunter Jagschies,Eva Lindskog,Karol Lacki,Parrish M. Galliher

Publisher: Elsevier

ISBN: 0128125527

Category: Technology & Engineering

Page: 1308

View: 4174

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Biopharmaceutical Processing: Development, Design, and Implementation of Manufacturing Processes covers bioprocessing from cell line development to bulk drug substances. The methods and strategies described are essential learning for every scientist, engineer or manager in the biopharmaceutical and vaccines industry. The integrity of the bioprocess ultimately determines the quality of the product in the biotherapeutics arena, and this book covers every stage including all technologies related to downstream purification and upstream processing fields. Economic considerations are included throughout, with recommendations for lowering costs and improving efficiencies. Designed for quick reference and easy accessibility of facts, calculations and guidelines, this book is an essential tool for industrial scientists and managers in the biopharmaceutical industry. Offers a comprehensive, go-to reference for daily work decisions Covers both upstream and downstream processes Includes case studies that emphasize financial outcomes Presents summaries, decision grids, graphs and overviews for quick reference

Current Developments in Biotechnology and Bioengineering

Production, Isolation and Purification of Industrial Products

Author: Ashok Pandey,Sangeeta Negi,Carlos Ricardo Soccol

Publisher: Elsevier

ISBN: 0444636730

Category: Science

Page: 886

View: 8471

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Current Developments in Biotechnology and Bioengineering: Production, Isolation and Purification of Industrial Products provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends, focusing on industrial biotechnology and bioengineering practices for the production of industrial products, such as enzymes, organic acids, biopolymers, and biosurfactants, and the processes for isolating and purifying them from a production medium. During the last few years, the tools of molecular biology and genetic and metabolic engineering have rendered tremendous improvements in the production of industrial products by fermentation. Structured by industrial product classifications, this book provides an overview of the current practice, status, and future potential for the production of these agents, along with reviews of the industrial scenario relating to their production. Provides information on industrial bioprocesses for the production of microbial products by fermentation Includes separation and purification processes of fermentation products Presents economic and feasibility assessments of the various processes and their scaling up Links biotechnology and bioengineering for industrial process development

Microbial Applications Vol.2

Biomedicine, Agriculture and Industry

Author: Vipin Chandra Kalia

Publisher: Springer

ISBN: 3319526693

Category: Science

Page: 336

View: 9556

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This contributed volume provides insights into multiple applications using microbes to promote productivity in agriculture, to produce biochemicals or to respond to challenges in biomedicine. It highlights the microbial production of nanocompounds with medical functionality alongside new anti-mycobacterial strategies, and introduces plant-growth-promoting Rhizobacteria as well as the correlation between biofilm formation and crop productivity. Further, the authors illustrate the green synthesis of biochemical compounds, such as hydroxamid acid or biosurfactants, using microbial and fungal enzymes. It inspires young researchers and experienced scientists in the field of microbiology to explore the combined use of green, white and red biotechnology for industrial purposes, which will be one of the central topics for future generations.

Comprehensive Biotechnology

Author: N.A

Publisher: Newnes

ISBN: 0080885047

Category: Science

Page: 5320

View: 2026

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The second edition of Comprehensive Biotechnology continues the tradition of the first inclusive work on this dynamic field with up-to-date and essential entries on the principles and practice of biotechnology. The integration of the latest relevant science and industry practice with fundamental biotechnology concepts is presented with entries from internationally recognized world leaders in their given fields. With two volumes covering basic fundamentals, and four volumes of applications, from environmental biotechnology and safety to medical biotechnology and healthcare, this work serves the needs of newcomers as well as established experts combining the latest relevant science and industry practice in a manageable format. It is a multi-authored work, written by experts and vetted by a prestigious advisory board and group of volume editors who are biotechnology innovators and educators with international influence. All six volumes are published at the same time, not as a series; this is not a conventional encyclopedia but a symbiotic integration of brief articles on established topics and longer chapters on new emerging areas. Hyperlinks provide sources of extensive additional related information; material authored and edited by world-renown experts in all aspects of the broad multidisciplinary field of biotechnology Scope and nature of the work are vetted by a prestigious International Advisory Board including three Nobel laureates Each article carries a glossary and a professional summary of the authors indicating their appropriate credentials An extensive index for the entire publication gives a complete list of the many topics treated in the increasingly expanding field

Biomass as Renewable Raw Material to Obtain Bioproducts of High-Tech Value

Author: Valentin I. Popa,Irina Volf

Publisher: Elsevier

ISBN: 0444637974

Category: Technology & Engineering

Page: 492

View: 1065

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Biomass as Renewable Raw Material to Obtain Bioproducts of High-tech Value examines the use of biomass as a raw material, including terrestrial and aquatic sources to obtain extracts (e.g. polyphenols), biofuels, and/or intermediates (furfural, levulinates) through chemical and biochemical processes. The book also covers the production of natural polymers using biomass and the biosynthetic process, cellulose modified by biochemical and chemical methods, and other biochemicals that can be used in the synthesis of various pharmaceuticals. Featuring case studies, discussions of sustainability, and nanomedical, biomedical, and pharmaceutical applications, Biomass as Renewable Raw Material to Obtain Bioproducts of High-tech Value is a crucial resource for biotechnologists, biochemical engineers, biochemists, microbiologists, and research students in these areas, as well as entrepreneurs, policy makers, stakeholders, and politicians. Reviews biomass resources and compounds with bioactive properties Describes chemical and biochemical processes for creating biofuels from biomass Outlines production of polysaccharides and cellulose derivatives Features applications in the fields of medicine and pharmacy

Novel Biodegradable Microbial Polymers

Author: E.A. Dawes

Publisher: Springer Science & Business Media

ISBN: 9400921292

Category: Nature

Page: 485

View: 2462

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The NATO Advanced Research Workshop from which this book derives was conceived during Biotec-88, the Second Spanish Conference on Biotechnology, held at Barcelona in June 1988. The President of the Conference, Dr. Ricardo Guerrero, had arranged sessions on bacterial polymers which included lectures by five invited participants who, together with Dr. Guerrero, became the Organizing Committee for a projected meeting that would focus attention upon the increasing international importance of novel biodegradable polymers. The proposal found favour with the NATO Science Committee and, with Dr. R. Clinton Fuller and Dr. Robert W. Lenz as the co-Directors, Dr. Edwin A. Dawes as the Proceedings Editor, and Dr. Hans G. Schlegel, Dr. Alexander J.B. Zehnder and Dr. Ricardo Guerrero as members of the Organizing Committee, the meeting quickly took shape. To Dr. Guerrero we owe the happy choice of Sitges for the venue, a pleasant coastal resort 36 kilometres from Barcelona, which proved ideal. The sessions were held at the Palau de Maricel in appropriately impressive surroundings, and invaluable local support was provided by Mr. Jordi Mas-Castella and by Ms. Merce Piqueras. Much of the preparatory work fell upon the broad shoulders of Mr. Edward Knee, whose efforts are deeply appreciated. The Organizing Committee hopes that this Workshop will prove to be the first of a series which will aim to keep abreast of a rapidly expanding and exciting area of research that is highly relevant to environmental and industrial interests.

The Metabolic Pathway Engineering Handbook

Fundamentals

Author: Christina Smolke

Publisher: CRC Press

ISBN: 9781439802977

Category: Medical

Page: 678

View: 4887

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This first volume of the Metabolic Pathway Engineering Handbook provides an overview of metabolic pathway engineering with a look towards the future. It discusses cellular metabolism, including transport processes inside the cell and energy generating reactions, as well as rare metabolic conversions. This volume also explores balances and reaction models, the regulation of metabolic pathways, and genome scale and multiscale modeling tools. It also covers developing appropriate hosts for metabolic engineering including the use of Escherichia coli, yeast, Bacillus Subtilis, Streptomyces, filamentous fungi, and mammalian cells using cell culture. Christine Smolke, who recently developed a novel way to churn out large quantities of drugs from genetically modified brewer’s yeast, is regarded as one of the most brilliant new minds in biomedical engineering. In this handbook, she brings together pioneering scientists from dozens of disciplines to provide a complete record of accomplishment in metabolic pathway engineering. With a wealth of cutting edge research and analysis, this work also serves as an invaluable resource for those seeking to add their own contributions. Organized by topic, this 3000 page reference is available as two volumes that can be purchased individually or as a set. For information on the complete handbook visit Cat No. 3923

Bioenergy Research: Advances and Applications

Author: Vijai G. Gupta,Maria Tuohy,Christian P Kubicek,Jack Saddler,Feng Xu

Publisher: Newnes

ISBN: 0444595643

Category: Technology & Engineering

Page: 500

View: 5506

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Bioenergy Research: Advances and Applications brings biology and engineering together to address the challenges of future energy needs. The book consolidates the most recent research on current technologies, concepts, and commercial developments in various types of widely used biofuels and integrated biorefineries, across the disciplines of biochemistry, biotechnology, phytology, and microbiology. All the chapters in the book are derived from international scientific experts in their respective research areas. They provide you with clear and concise information on both standard and more recent bioenergy production methods, including hydrolysis and microbial fermentation. Chapters are also designed to facilitate early stage researchers, and enables you to easily grasp the concepts, methodologies and application of bioenergy technologies. Each chapter in the book describes the merits and drawbacks of each technology as well as its usefulness. The book provides information on recent approaches to graduates, post-graduates, researchers and practitioners studying and working in field of the bioenergy. It is an invaluable information resource on biomass-based biofuels for fundamental and applied research, catering to researchers in the areas of bio-hydrogen, bioethanol, bio-methane and biorefineries, and the use of microbial processes in the conversion of biomass into biofuels. Reviews all existing and promising technologies for production of advanced biofuels in addition to bioenergy policies and research funding Cutting-edge research concepts for biofuels production using biological and biochemical routes, including microbial fuel cells Includes production methods and conversion processes for all types of biofuels, including bioethanol and biohydrogen, and outlines the pros and cons of each

Biodegradable Polyesters

Author: Stoyko Fakirov

Publisher: John Wiley & Sons

ISBN: 3527656979

Category: Technology & Engineering

Page: 368

View: 5911

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Collating otherwise hard-to-get and recently acquired knowledge in one work, this is a comprehensive reference on the synthesis, properties, characterization, and applications of this eco-friendly class of plastics. A group of internationally renowned researchers offer their first-hand experience and knowledge, dealing exclusively with those biodegradable polyesters that have become increasingly important over the past two decades due to environmental concerns on the one hand and newly-devised applications in the biomedical field on the other. The result is an unparalleled overview for the industrial chemist and materials scientist, as well as for developers and researchers in industry and academia alike.

Biopolyesters

Author: Wolfgang Babel,Alexander Steinbüchel

Publisher: Springer

ISBN: 3540400214

Category: Technology & Engineering

Page: 342

View: 6432

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Living systems synthesize seven different classes of polymers. They provide structure and form for cells and organisms, function as catalysts and energy storage and carry the genetic information. All these polymers possess technically interesting properties. Some of these biopolymers are already used commercially. This special volume of Advances in Biochemical Engineering/Biotechnology comprises 10 chapters. It gives an overview of the water insoluble biopolyesters, in particular of the microbially synthesized poly-hydroxyalkanoate (PHA) family. It reports the state of the art of metabolism, regulation and genetic background, the latest advances made in genetic optimization of bacteria, "construction" of transgenic plants and in vitro synthesis by means of purified enzymes. Furthermore, it describes relevant technologies and evaluates perspectives concerning increasing the economic viability and competitiveness of PHA and discusses applications in medicine, packaging, food and other fields.

Compostable Polymer Materials

Author: Ewa Rudnik

Publisher: Elsevier

ISBN: 9780080560847

Category: Technology & Engineering

Page: 224

View: 8540

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Compostable Polymer Materials deals with an environmentally important family of polymers designed to be disposed of in industrial and municipal compost facilities after their useful life. These compostable plastics undergo degradation and leave no visible, distinguishable or toxic residue. Environmental concerns and legislative measures taken in different regions of the world make composting an increasingly attractive route for the disposal of redundant polymers. This book provides up–to-date results and information about compostable polymer materials in a coherent and comprehensive manner. It covers the entire spectrum of preparation, properties, degradation, and environmental issues. The emphasis is on recent studies concerning compostability and ecotoxicological assessment of polymer materials-–important issues from the ecological point of view. Moreover, the thermal behavior of compostable polymers is described. Their price evolution over the past decade, an estimation of the market and future perspectives are presented. Focus on the composting process, compostability standards, compost quality and composting studies Coherent and uniformly presented information about methods of preparation; properties, processing and applications Up-to-date information on ecotoxicity testing and studies of polymers Overview of thermal stability and thermal degradation process of compostable polymer materials Presents future perspectives of compostable polymers, including evolution of price during last decade Information about waste management evolution in Europe, USA and Asia (China) with emphasis on composting during the last decade