Linear and Generalized Linear Mixed Models and Their Applications

Author: Jiming Jiang

Publisher: Springer Science & Business Media

ISBN: 0387479465

Category: Mathematics

Page: 257

View: 7565

DOWNLOAD NOW »

This book covers two major classes of mixed effects models, linear mixed models and generalized linear mixed models. It presents an up-to-date account of theory and methods in analysis of these models as well as their applications in various fields. The book offers a systematic approach to inference about non-Gaussian linear mixed models. Furthermore, it includes recently developed methods, such as mixed model diagnostics, mixed model selection, and jackknife method in the context of mixed models. The book is aimed at students, researchers and other practitioners who are interested in using mixed models for statistical data analysis.

Linear Mixed Models for Longitudinal Data

Author: Geert Verbeke,Geert Molenberghs

Publisher: Springer Science & Business Media

ISBN: 1441903003

Category: Mathematics

Page: 570

View: 686

DOWNLOAD NOW »

This book provides a comprehensive treatment of linear mixed models for continuous longitudinal data. Next to model formulation, this edition puts major emphasis on exploratory data analysis for all aspects of the model, such as the marginal model, subject-specific profiles, and residual covariance structure. Further, model diagnostics and missing data receive extensive treatment. Sensitivity analysis for incomplete data is given a prominent place. Most analyses were done with the MIXED procedure of the SAS software package, but the data analyses are presented in a software-independent fashion.

Correlated Data Analysis: Modeling, Analytics, and Applications

Author: Xue-Kun Song

Publisher: Springer Science & Business Media

ISBN: 0387713921

Category: Mathematics

Page: 346

View: 2858

DOWNLOAD NOW »

This book covers recent developments in correlated data analysis, using the class of dispersion models as marginal components in the formulation of joint models for correlated data. Much new material is covered here that you won’t find elsewhere.

Correlated Data Analysis: Modeling, Analytics, and Applications

Author: Peter X. -K. Song

Publisher: Springer Science & Business Media

ISBN: 038771393X

Category: Mathematics

Page: 352

View: 3646

DOWNLOAD NOW »

This book covers recent developments in correlated data analysis. It utilizes the class of dispersion models as marginal components in the formulation of joint models for correlated data. This enables the book to cover a broader range of data types than the traditional generalized linear models. The reader is provided with a systematic treatment for the topic of estimating functions, and both generalized estimating equations (GEE) and quadratic inference functions (QIF) are studied as special cases. In addition to the discussions on marginal models and mixed-effects models, this book covers new topics on joint regression analysis based on Gaussian copulas.

Vector Generalized Linear and Additive Models

With an Implementation in R

Author: Thomas W. Yee

Publisher: Springer

ISBN: 149392818X

Category: Mathematics

Page: 589

View: 3804

DOWNLOAD NOW »

This book presents a greatly enlarged statistical framework compared to generalized linear models (GLMs) with which to approach regression modelling. Comprising of about half-a-dozen major classes of statistical models, and fortified with necessary infrastructure to make the models more fully operable, the framework allows analyses based on many semi-traditional applied statistics models to be performed as a coherent whole. Since their advent in 1972, GLMs have unified important distributions under a single umbrella with enormous implications. However, GLMs are not flexible enough to cope with the demands of practical data analysis. And data-driven GLMs, in the form of generalized additive models (GAMs), are also largely confined to the exponential family. The methodology here and accompanying software (the extensive VGAM R package) are directed at these limitations and are described comprehensively for the first time in one volume. This book treats distributions and classical models as generalized regression models, and the result is a much broader application base for GLMs and GAMs. The book can be used in senior undergraduate or first-year postgraduate courses on GLMs or categorical data analysis and as a methodology resource for VGAM users. In the second part of the book, the R package VGAM allows readers to grasp immediately applications of the methodology. R code is integrated in the text, and datasets are used throughout. Potential applications include ecology, finance, biostatistics, and social sciences. The methodological contribution of this book stands alone and does not require use of the VGAM package.

Statistics for High-Dimensional Data

Methods, Theory and Applications

Author: Peter Bühlmann,Sara van de Geer

Publisher: Springer Science & Business Media

ISBN: 364220192X

Category: Mathematics

Page: 558

View: 1985

DOWNLOAD NOW »

Modern statistics deals with large and complex data sets, and consequently with models containing a large number of parameters. This book presents a detailed account of recently developed approaches, including the Lasso and versions of it for various models, boosting methods, undirected graphical modeling, and procedures controlling false positive selections. A special characteristic of the book is that it contains comprehensive mathematical theory on high-dimensional statistics combined with methodology, algorithms and illustrations with real data examples. This in-depth approach highlights the methods’ great potential and practical applicability in a variety of settings. As such, it is a valuable resource for researchers, graduate students and experts in statistics, applied mathematics and computer science.

Plane Answers to Complex Questions

The Theory of Linear Models

Author: Ronald Christensen

Publisher: Springer Science & Business Media

ISBN: 1475724772

Category: Mathematics

Page: 453

View: 4154

DOWNLOAD NOW »

The second edition of Plane Answers has many additions and a couple of deletions. New material includes additional illustrative examples in Ap pendices A and B and Chapters 2 and 3, as well as discussions of Bayesian estimation, near replicate lack of fit tests, testing the independence assump tion, testing variance components, the interblock analysis for balanced in complete block designs, nonestimable constraints, analysis of unreplicated experiments using normal plots, tensors, and properties of Kronecker prod ucts and Vee operators. The book contains an improved discussion of the relation between ANOVA and regression, and an improved presentation of general Gauss-Markov models. The primary material that has been deleted are the discussions of weighted means and of log-linear models. The mate rial on log-linear models was included in Christensen (1990b), so it became redundant here. Generally, I have tried to clean up the presentation of ideas wherever it seemed obscure to me. Much of the work on the second edition was done while on sabbatical at the University of Canterbury in Christchurch, New Zealand. I would par ticularly like to thank John Deely for arranging my sabbatical. Through their comments and criticisms, four people were particularly helpful in con structing this new edition. I would like to thank Wes Johnson, Snehalata Huzurbazar, Ron Butler, and Vance Berger.

Foundations of Linear and Generalized Linear Models

Author: Alan Agresti

Publisher: John Wiley & Sons

ISBN: 1118730038

Category: Mathematics

Page: 472

View: 3689

DOWNLOAD NOW »

"This book presents an overview of the foundations and the key ideas and results of linear and generalized linear models under one cover. Written by a prolific academic, researcher, and textbook writer, Foundations of Linear and Generalized Linear Modelsis soon to become the gold standard by which all existing textbooks on the topic will be compared. While the emphasis is clearly and succinctly on theoretical underpinnings, applications in "R" are presented when they help to elucidate the content or promote practical model building. Each chapter contains approximately 15-20 exercises, primarily for readers to practice and extend the theory, but, also to assimilate the ideas by doing some data analysis. The carefully crafted models and examples convey basic concepts and do not get mired down in non-trivial considerations. An author-maintained web site includes, among other numerous pedagogical supplements, analyses that parallel the "R" routines from the book in SAS, SPSS and Stata"--

Mixed Effects Models for the Population Approach

Models, Tasks, Methods and Tools

Author: Marc Lavielle

Publisher: CRC Press

ISBN: 1482226502

Category: Mathematics

Page: 383

View: 9937

DOWNLOAD NOW »

Wide-Ranging Coverage of Parametric Modeling in Linear and Nonlinear Mixed Effects Models Mixed Effects Models for the Population Approach: Models, Tasks, Methods and Tools presents a rigorous framework for describing, implementing, and using mixed effects models. With these models, readers can perform parameter estimation and modeling across a whole population of individuals at the same time. Easy-to-Use Techniques and Tools for Real-World Data Modeling The book first shows how the framework allows model representation for different data types, including continuous, categorical, count, and time-to-event data. This leads to the use of generic methods, such as the stochastic approximation of the EM algorithm (SAEM), for modeling these diverse data types. The book also covers other essential methods, including Markov chain Monte Carlo (MCMC) and importance sampling techniques. The author uses publicly available software tools to illustrate modeling tasks. Methods are implemented in Monolix, and models are visually explored using Mlxplore and simulated using Simulx. Careful Balance of Mathematical Representation and Practical Implementation This book takes readers through the whole modeling process, from defining/creating a parametric model to performing tasks on the model using various mathematical methods. Statisticians and mathematicians will appreciate the rigorous representation of the models and theoretical properties of the methods while modelers will welcome the practical capabilities of the tools. The book is also useful for training and teaching in any field where population modeling occurs.

Linear Models with R, Second Edition

Author: Julian J. Faraway

Publisher: CRC Press

ISBN: 1439887349

Category: Mathematics

Page: 286

View: 6769

DOWNLOAD NOW »

A Hands-On Way to Learning Data Analysis Part of the core of statistics, linear models are used to make predictions and explain the relationship between the response and the predictors. Understanding linear models is crucial to a broader competence in the practice of statistics. Linear Models with R, Second Edition explains how to use linear models in physical science, engineering, social science, and business applications. The book incorporates several improvements that reflect how the world of R has greatly expanded since the publication of the first edition. New to the Second Edition Reorganized material on interpreting linear models, which distinguishes the main applications of prediction and explanation and introduces elementary notions of causality Additional topics, including QR decomposition, splines, additive models, Lasso, multiple imputation, and false discovery rates Extensive use of the ggplot2 graphics package in addition to base graphics Like its widely praised, best-selling predecessor, this edition combines statistics and R to seamlessly give a coherent exposition of the practice of linear modeling. The text offers up-to-date insight on essential data analysis topics, from estimation, inference, and prediction to missing data, factorial models, and block designs. Numerous examples illustrate how to apply the different methods using R.

Models for Discrete Longitudinal Data

Author: Geert Molenberghs,Geert Verbeke

Publisher: Springer Science & Business Media

ISBN: 9780387251448

Category: Mathematics

Page: 683

View: 9233

DOWNLOAD NOW »

This book provides a comprehensive treatment on modeling approaches for non-Gaussian repeated measures, possibly subject to incompleteness. The authors begin with models for the full marginal distribution of the outcome vector. This allows model fitting to be based on maximum likelihood principles, immediately implying inferential tools for all parameters in the models. At the same time, they formulate computationally less complex alternatives, including generalized estimating equations and pseudo-likelihood methods. They then briefly introduce conditional models and move on to the random-effects family, encompassing the beta-binomial model, the probit model and, in particular the generalized linear mixed model. Several frequently used procedures for model fitting are discussed and differences between marginal models and random-effects models are given attention The authors consider a variety of extensions, such as models for multivariate longitudinal measurements, random-effects models with serial correlation, and mixed models with non-Gaussian random effects. They sketch the general principles for how to deal with the commonly encountered issue of incomplete longitudinal data. The authors critique frequently used methods and propose flexible and broadly valid methods instead, and conclude with key concepts of sensitivity analysis. Without putting too much emphasis on software, the book shows how the different approaches can be implemented within the SAS software package. The text is organized so the reader can skip the software-oriented chapters and sections without breaking the logical flow. Geert Molenberghs is Professor of Biostatistics at the Universiteit Hasselt in Belgium and has published methodological work on surrogate markers in clinical trials, categorical data, longitudinal data analysis, and the analysis of non-response in clinical and epidemiological studies. He served as Joint Editor for Applied Statistics (2001–2004) and as Associate Editor for several journals, including Biometrics and Biostatistics. He was President of the International Biometric Society (2004–2005). He was elected Fellow of the American Statistical Association and received the Guy Medal in Bronze from the Royal Statistical Society. Geert Verbeke is Professor of Biostatistics at the Biostatistical Centre of the Katholieke Universiteit Leuven in Belgium. He has published a number of methodological articles on various aspects of models for longitudinal data analyses, with particular emphasis on mixed models. Geert Verbeke is Past President of the Belgian Region of the International Biometric Society, International Program Chair for the International Biometric Conference in Montreal (2006), and Joint Editor of the Journal of the Royal Statistical Society, Series A (2005–2008). He has served as Associate Editor for several journals including Biometrics and Applied Statistics. The authors also wrote a monograph on linear mixed models for longitudinal data (Springer, 2000) and received the American Statistical Association's Excellence in Continuing Education Award, based on short courses on longitudinal and incomplete data at the Joint Statistical Meetings of 2002 and 2004.

Advances in Statistical Methods for Genetic Improvement of Livestock

Author: Daniel Gianola,Keith Hammond

Publisher: Springer Science & Business Media

ISBN: 3642744877

Category: Technology & Engineering

Page: 534

View: 2790

DOWNLOAD NOW »

Developments in statistics and computing as well as their application to genetic improvement of livestock gained momentum over the last 20 years. This text reviews and consolidates the statistical foundations of animal breeding. This text will prove useful as a reference source to animal breeders, quantitative geneticists and statisticians working in these areas. It will also serve as a text in graduate courses in animal breeding methodology with prerequisite courses in linear models, statistical inference and quantitative genetics.

Bayesian and Frequentist Regression Methods

Author: Jon Wakefield

Publisher: Springer Science & Business Media

ISBN: 1441909257

Category: Mathematics

Page: 697

View: 3989

DOWNLOAD NOW »

Bayesian and Frequentist Regression Methods provides a modern account of both Bayesian and frequentist methods of regression analysis. Many texts cover one or the other of the approaches, but this is the most comprehensive combination of Bayesian and frequentist methods that exists in one place. The two philosophical approaches to regression methodology are featured here as complementary techniques, with theory and data analysis providing supplementary components of the discussion. In particular, methods are illustrated using a variety of data sets. The majority of the data sets are drawn from biostatistics but the techniques are generalizable to a wide range of other disciplines.

The Elements of Statistical Learning

Data Mining, Inference, and Prediction

Author: Trevor Hastie,Robert Tibshirani,Jerome H. Friedman

Publisher: Springer Science & Business Media

ISBN: 9780387952840

Category: Mathematics

Page: 533

View: 2818

DOWNLOAD NOW »

This book describes the important ideas in a common conceptual framework. While the approach is statistical, the emphasis is on concepts rather than mathematics. Many examples are given, with a liberal use of color graphics. It should be a valuable resource for statisticians and anyone interested in data mining in science or industry.

Linear Mixed-Effects Models Using R

A Step-by-Step Approach

Author: Andrzej Gałecki,Tomasz Burzykowski

Publisher: Springer Science & Business Media

ISBN: 1461439000

Category: Mathematics

Page: 542

View: 5306

DOWNLOAD NOW »

Linear mixed-effects models (LMMs) are an important class of statistical models that can be used to analyze correlated data. Such data are encountered in a variety of fields including biostatistics, public health, psychometrics, educational measurement, and sociology. This book aims to support a wide range of uses for the models by applied researchers in those and other fields by providing state-of-the-art descriptions of the implementation of LMMs in R. To help readers to get familiar with the features of the models and the details of carrying them out in R, the book includes a review of the most important theoretical concepts of the models. The presentation connects theory, software and applications. It is built up incrementally, starting with a summary of the concepts underlying simpler classes of linear models like the classical regression model, and carrying them forward to LMMs. A similar step-by-step approach is used to describe the R tools for LMMs. All the classes of linear models presented in the book are illustrated using real-life data. The book also introduces several novel R tools for LMMs, including new class of variance-covariance structure for random-effects, methods for influence diagnostics and for power calculations. They are included into an R package that should assist the readers in applying these and other methods presented in this text.

Statistical Models in Epidemiology, the Environment, and Clinical Trials

Author: M.Elizabeth Halloran,Donald Berry

Publisher: Springer Science & Business Media

ISBN: 9780387989242

Category: Medical

Page: 283

View: 1564

DOWNLOAD NOW »

This IMA Volume in Mathematics and its Applications STATISTICAL MODELS IN EPIDEMIOLOGY, THE ENVIRONMENT,AND CLINICAL TRIALS is a combined proceedings on "Design and Analysis of Clinical Trials" and "Statistics and Epidemiology: Environment and Health. " This volume is the third series based on the proceedings of a very successful 1997 IMA Summer Program on "Statistics in the Health Sciences. " I would like to thank the organizers: M. Elizabeth Halloran of Emory University (Biostatistics) and Donald A. Berry of Duke University (Insti tute of Statistics and Decision Sciences and Cancer Center Biostatistics) for their excellent work as organizers of the meeting and for editing the proceedings. I am grateful to Seymour Geisser of University of Minnesota (Statistics), Patricia Grambsch, University of Minnesota (Biostatistics); Joel Greenhouse, Carnegie Mellon University (Statistics); Nicholas Lange, Harvard Medical School (Brain Imaging Center, McLean Hospital); Barry Margolin, University of North Carolina-Chapel Hill (Biostatistics); Sandy Weisberg, University of Minnesota (Statistics); Scott Zeger, Johns Hop kins University (Biostatistics); and Marvin Zelen, Harvard School of Public Health (Biostatistics) for organizing the six weeks summer program. I also take this opportunity to thank the National Science Foundation (NSF) and the Army Research Office (ARO), whose financial support made the workshop possible. Willard Miller, Jr.

Generalized Linear Models

with Applications in Engineering and the Sciences

Author: Raymond H. Myers,Douglas C. Montgomery,G. Geoffrey Vining,Timothy J. Robinson

Publisher: John Wiley & Sons

ISBN: 0470556978

Category: Mathematics

Page: 544

View: 303

DOWNLOAD NOW »

Praise for the First Edition "The obvious enthusiasm of Myers, Montgomery, and Vining and their reliance on their many examples as a major focus of their pedagogy make Generalized Linear Models a joy to read. Every statistician working in any area of applied science should buy it and experience the excitement of these new approaches to familiar activities." —Technometrics Generalized Linear Models: With Applications in Engineering and the Sciences, Second Edition continues to provide a clear introduction to the theoretical foundations and key applications of generalized linear models (GLMs). Maintaining the same nontechnical approach as its predecessor, this update has been thoroughly extended to include the latest developments, relevant computational approaches, and modern examples from the fields of engineering and physical sciences. This new edition maintains its accessible approach to the topic by reviewing the various types of problems that support the use of GLMs and providing an overview of the basic, related concepts such as multiple linear regression, nonlinear regression, least squares, and the maximum likelihood estimation procedure. Incorporating the latest developments, new features of this Second Edition include: A new chapter on random effects and designs for GLMs A thoroughly revised chapter on logistic and Poisson regression, now with additional results on goodness of fit testing, nominal and ordinal responses, and overdispersion A new emphasis on GLM design, with added sections on designs for regression models and optimal designs for nonlinear regression models Expanded discussion of weighted least squares, including examples that illustrate how to estimate the weights Illustrations of R code to perform GLM analysis The authors demonstrate the diverse applications of GLMs through numerous examples, from classical applications in the fields of biology and biopharmaceuticals to more modern examples related to engineering and quality assurance. The Second Edition has been designed to demonstrate the growing computational nature of GLMs, as SAS®, Minitab®, JMP®, and R software packages are used throughout the book to demonstrate fitting and analysis of generalized linear models, perform inference, and conduct diagnostic checking. Numerous figures and screen shots illustrating computer output are provided, and a related FTP site houses supplementary material, including computer commands and additional data sets. Generalized Linear Models, Second Edition is an excellent book for courses on regression analysis and regression modeling at the upper-undergraduate and graduate level. It also serves as a valuable reference for engineers, scientists, and statisticians who must understand and apply GLMs in their work.

Multivariate Generalized Linear Mixed Models Using R

Author: Damon Mark Berridge,Robert Crouchley

Publisher: CRC Press

ISBN: 1439813272

Category: Mathematics

Page: 304

View: 9191

DOWNLOAD NOW »

Multivariate Generalized Linear Mixed Models Using R presents robust and methodologically sound models for analyzing large and complex data sets, enabling readers to answer increasingly complex research questions. The book applies the principles of modeling to longitudinal data from panel and related studies via the Sabre software package in R. A Unified Framework for a Broad Class of Models The authors first discuss members of the family of generalized linear models, gradually adding complexity to the modeling framework by incorporating random effects. After reviewing the generalized linear model notation, they illustrate a range of random effects models, including three-level, multivariate, endpoint, event history, and state dependence models. They estimate the multivariate generalized linear mixed models (MGLMMs) using either standard or adaptive Gaussian quadrature. The authors also compare two-level fixed and random effects linear models. The appendices contain additional information on quadrature, model estimation, and endogenous variables, along with SabreR commands and examples. Improve Your Longitudinal Study In medical and social science research, MGLMMs help disentangle state dependence from incidental parameters. Focusing on these sophisticated data analysis techniques, this book explains the statistical theory and modeling involved in longitudinal studies. Many examples throughout the text illustrate the analysis of real-world data sets. Exercises, solutions, and other material are available on a supporting website.

Extending the Linear Model with R

Generalized Linear, Mixed Effects and Nonparametric Regression Models

Author: Julian J. Faraway

Publisher: CRC Press

ISBN: 9780203492284

Category: Mathematics

Page: 312

View: 4898

DOWNLOAD NOW »

Linear models are central to the practice of statistics and form the foundation of a vast range of statistical methodologies. Julian J. Faraway's critically acclaimed Linear Models with R examined regression and analysis of variance, demonstrated the different methods available, and showed in which situations each one applies. Following in those footsteps, Extending the Linear Model with R surveys the techniques that grow from the regression model, presenting three extensions to that framework: generalized linear models (GLMs), mixed effect models, and nonparametric regression models. The author's treatment is thoroughly modern and covers topics that include GLM diagnostics, generalized linear mixed models, trees, and even the use of neural networks in statistics. To demonstrate the interplay of theory and practice, throughout the book the author weaves the use of the R software environment to analyze the data of real examples, providing all of the R commands necessary to reproduce the analyses. All of the data described in the book is available at http://people.bath.ac.uk/jjf23/ELM/ Statisticians need to be familiar with a broad range of ideas and techniques. This book provides a well-stocked toolbox of methodologies, and with its unique presentation of these very modern statistical techniques, holds the potential to break new ground in the way graduate-level courses in this area are taught.