Classics in Stereoselective Synthesis

Author: Erick M. Carreira,Lisbet Kvaerno

Publisher: John Wiley & Sons

ISBN: 9783527324521

Category: Science

Page: 632

View: 4388


This book provides a noteworthy compilation of the groundbreaking methods of stereoselective synthesis, belonging to the repertoire of every modern practitioner of synthetic organic chemistry. The general principles underlying these processes are highlighted as they form the basis for the rapid and continuing developments in the field. The work also features illustrative examples of drug and natural product syntheses, resulting in a rich source of stimulating ideas for the efficient use of asymmetric reactions in the construction of stereochemically complex structures. From the contents: "Macrocyclic stereocontrol "Carbonyl addition reactions "alpha-Functionalization of enolates "Aldol and allylation reactions "Chiral acetals "Alkene hydroboration, reduction, and oxidation "Additions to C=N bonds and synthesis of amino acids "Conjugate additions "Chiral carbanions "Metal-catalyzed allylations "Cyclopropanations and CH-insertion reactions "Sigmatropic rearrangements "Diels-Alder and hetero-Diels-Alder reactions "[3+2]- and [2+2]-cycloaddition reactions

Classics in Spectroscopy

Author: Stefan Berger,Dieter Sicker

Publisher: John Wiley & Sons

ISBN: 9783527325160

Category: Science

Page: 645

View: 9228


The first book of its kind to describe the art of NMR using everyday examples. This textbook will not only fascinate students wanting to learn about the topic, but also those experienced analytical chemists who are still inspired by their profession. The contents provide for easy reading by using natural products that everyone knows, such as caffeine, backed by an attractive layout with many pictures to visualize the topics. In addition, an in-depth analytical part makes the book a valuable teaching tool, or for self-learning using the questions and answers at the end of each chapter.

Silver in Organic Chemistry

Author: Michael Harmata

Publisher: John Wiley & Sons

ISBN: 9781118057865

Category: Science

Page: 402

View: 6523


The first authoritative book on using silver cations in organic chemistry—for catalysis and more! With more sophisticated catalytic methodologies fueling a resurgence in the study of cation-based chemistry, gold and platinum have stepped to the fore as the unique agents used to create new chemical reactions. Although these metals have become a primary focus of researchers in the field, another coinage metal that is often overlooked—but is as powerful as the others—is silver, a far less costly alternative to gold and platinum in aiding the development of new reactions. Making a strong case for the use of silver as a catalyst and structural element in organometal constructs, this authoritative book is the first to explore the benefits of using silver in organic chemistry by taking a close look at silver’s unique reactivity and structural characteristics for the development of new methods and materials. Silver in Organic Chemistry is: The first book to address catalysis using silver, whose use in organic chemistry is on the verge of exploding A resource for researchers wishing to do chemistry with silver cations, an area that stands in the shadow of gold chemistry, but still glistens, demonstrating that all that glitters is not gold—sometimes it’s silver! A guide for “first attempts” in working with silver cations Edited by a very well-respected, highly visible authority in this field Silver in Organic Chemistry promotes further scientific discussion by offering important new ways to examine the future possibilities of an emerging field. By elevating the importance of silver chemistry, this thought-provoking guide illustrates how this versatile metal can become an increasingly significant player in opening the door to new catalytic organic reactions and new organometal materials.

Classics in Hydrocarbon Chemistry

Syntheses, Concepts, Perspectives

Author: Henning Hopf

Publisher: Wiley-VCH


Category: Science

Page: 547

View: 756


Brings together many of the most important advances in organic chemistry of the last century and can be read at several levels.

Classics in Total Synthesis III

Further Targets, Strategies, Methods

Author: K. C. Nicolaou,Jason S. Chen

Publisher: John Wiley & Sons

ISBN: 3527329579

Category: Science

Page: 746

View: 632


A wonderful tool for learning and teaching, and a must-have for all current and future organic, medicinal and biological chemists. --Book Jacket.

Organoselenium Chemistry

Synthesis and Reactions

Author: Thomas Wirth

Publisher: John Wiley & Sons

ISBN: 3527641955

Category: Science

Page: 462

View: 836


Selenium-based methods in synthetic chemistry have developed rapidly over the past years and are now offering highly useful tools for organic synthesis. Filling the gap for a comprehensive handbook and ready reference, this book covers all modern developments within the field, including biochemical aspects. The chemistry chapters are organized according to the different reactivities of various selenium compounds and reagents, with each chapter dealing with a special reaction type. Also includes a table with 77Se NMR shifts to aid in practical problems. From the Contents: * Electrophilic and Nucleophilic Selenium * Selenium Compounds in Radical Reactions * Selenium-Stabilized Carbanions * Selenium Compounds with Valency Higher than Two * Selenocarbonyls * Selenoxide Elimination and [2,3]-Sigmatropic Rearrangement * Selenium Compounds as Ligands and Catalysts * Biological and Biochemical Aspects of Selenium Compounds

Strategies and Tactics in Organic Synthesis

Author: Michael Harmata

Publisher: Gulf Professional Publishing

ISBN: 9780124502864

Category: Science

Page: 512

View: 9640


This title provides a forum for investigators to discuss their approach to the science and art of organic synthesis in a unique way. It provides a window into the world of design, function and synthesis that is at the leading edge of the molecular frontier.

Molekülorbitale und Reaktionen organischer Verbindungen

Author: Ian Fleming

Publisher: John Wiley & Sons

ISBN: 3527330690

Category: Chemical bonds

Page: 399

View: 6190


Der lang erwartete Nachfolger des Klassikers "Grenzorbitale und Reaktionen organischer Verbindungen". Die Molekülorbitalheorie wird einfach, ohne komplizierte mathematische Formeln und mit vielen illustrativen Beispielen erklärt.

Stereochemistry and Stereoselective Synthesis

An Introduction

Author: Mihály Nógrádi,László Poppe,József Nagy,Gábor Hornyánszky,Zoltán Boros

Publisher: John Wiley & Sons

ISBN: 3527696318

Category: Science

Page: 280

View: 4788


Written by a well-respected and experienced author, this textbook fills the gap for a concise introduction to the key concepts of organic stereochemistry and the most important classical and modern methods in stereoselective synthesis. The concepts are extensively illustrated in color, with practical examples and question-answer sets to help consolidate the reader's knowledge. In addition, animations are available from the Wiley website. A must-have for students in chemistry, biochemistry, and life sciences, as well as researchers in pharmaceutical and agrochemical companies in need of a quick introduction to the field.

Studies in Natural Products Chemistry

Stereoselective Synthesis (Part F)

Author: Atta-ur- Rahman

Publisher: Elsevier

ISBN: 1483100979

Category: Science

Page: 730

View: 7905


Studies in Natural Products Chemistry, Volume 10: Stereoselective Synthesis (Part F) is a collection of articles about studies on important organic molecules. The book covers studies such as that on the synthesis of cembranes as well as its natural occurrence and bioactivity; the stereoselective synthesis of Vitamin D; the synthesis of isoquinolinequinone antibiotics; and the nucleophilic addition chemistry of polyunsaturated carbonyl compounds. Also covered in the book are subjects such as developments in the synthesis of medium ring ethers; the biological properties, chemistry, and synthesis of didemnins; and natural products synthesis based on novel ring transformation. The text is recommended for organic chemists who would like to know more about the progresses in the study of important organic molecules and their implications in different fields.

Organische Chemie

Author: Vollhardt,Neil E. Schore

Publisher: Wiley-VCH

ISBN: 9783527313808

Category: Science

Page: 1570

View: 6961


Besser Konzepte und Ideen der organischen Chemie verstehen, als eine Vielzahl von Fakten auswendig beherrschen! Diesem Motto bleibt der "Vollhardt/Schore" auch in der neuesten Auflage treu. Das neu gestaltete Layout, beispielhaft gelöste Übungsaufgaben und die deutlich erweiterten Verständnisübungen führen einprägsam an die Methodik zur Lösung organisch-chemischer Probleme heran. So werden nicht nur die stofflichen Grundlagen der organischen Chemie, sondern auch das "Gewusst wie" fast schon spielerisch vermittelt. Nicht nur für Chemiestudenten, auch für Biochemiker, Pharmazeuten, Biologen und Mediziner ist der "Vollhardt/Schore" der fachliche Grundstock für die organische Chemie.

All In - Tausend Augenblicke

Author: Emma Scott


ISBN: 3736308558

Category: Fiction

Page: 425

View: 6136


"Wir haben Augenblicke. Tausende von Augenblicken. Lass uns jeden davon bis zum Letzten auskosten." Kacey Dawson wollte immer nur Musik machen. Aber selbst der kometenhafte Aufstieg ihrer Band kann sie nicht über ihre innere Einsamkeit hinwegtäuschen. Nach einem desaströsen Konzert in Las Vegas wacht sie mit dem schlimmsten Kater ihres Lebens auf der Couch ihres jungen Chauffeurs Jonah Fletcher auf. Er bietet ihr eine Auszeit von ihrem Leben als Rockstar und den Halt, den sie immer gesucht hat. Schon nach kürzester Zeit verspürt Kacey eine tiefe Verbundenheit zu Jonah - es ist, als wäre er der Teil von ihr, der immer fehlte. Doch Jonah hat ein Geheimnis - so groß und herzzerreißend, dass es ihre Welt für immer auf den Kopf zu stellen droht ... "Eine zutiefst berührende Liebesgeschichte, die man nie wieder vergisst - so real, so wunderschön geschrieben, so perfekt." Totally Booked Blog Band 1 des All-In-Duetts

Chirality in Drug Design and Development

Author: Indra K. Reddy,Reza Mehvar

Publisher: CRC Press

ISBN: 0824751094

Category: Science

Page: 1200

View: 1879


Covering every essential element in the development of chiral products, this reference provides a solid overview of the formulation, biopharmaceutical characteristics, and regulatory issues impacting the production of these pharmaceuticals. It supports researchers as they evaluate the pharmacodynamic, pharmacokinetic, and toxicological characteristics of specific enantiomers and chiral drug compounds and addresses in one convenient reference all the major challenges pertaining to drug chirality that have been neglected in the literature. Chirality in Drug Design and Development collects the latest studies from an interdisciplinary team of experts on chiral drug design.

Six-Membered Transition States in Organic Synthesis

Author: Jaemoon Yang

Publisher: John Wiley & Sons

ISBN: 9780470199046

Category: Science

Page: 224

View: 1484


This book furthers readers’ understanding of the amazing features of six-membered transition states in stereoselective organic reactions. Comprehensive and logically organized, it covers reactions classified in four categories: [3,3]-sigmatropic rearrangements, aldol reactions, metal allylation reactions, and stereoselective reductions. There is a thorough discussion of each reaction category, along with computational studies that support a proposal of a six-membered state. The book assists professors, researchers, and students in proposing reasonable transition states for the description of newly discovered stereoselective reactions.

Organic Synthesis

State of the Art 2007 - 2009

Author: Douglass Taber

Publisher: Oxford University Press

ISBN: 0190208775

Category: Science

Page: 252

View: 7404


Organic synthesis is a vibrant and rapidly evolving field; we can now cyclize amines directly onto alkenes. Like the first two books in this series, Organic Synthesis: State of the Art 2003-2005 and Organic Synthesis: State of the Art 2005-2007, this reference leads readers quickly to the most important recent developments. Two years of Taber's popular weekly online column, "Organic Chemistry Highlights", as featured on the website, are consolidated here, with cumulative indices of all three volumes in this series. Important topics that are covered range from powerful new methods for C-C bond construction to asymmetric organocatalysis and direct C-H functionalization. This go-to reference focuses on the most important recent developments in organic synthesis, and includes a succinct analysis of the significance and applicability of each new synthetic method. It details and analyzes more than twenty complex total syntheses, including the Sammakia synthesis of the Macrolide RK-397, the Ley synthesis of Rapamycin, and the Kobayashi synthesis of (-)-Norzoanthamine.


Synthesis and Applications

Author: Vivek Polshettiwar,Tewodros Asefa

Publisher: John Wiley & Sons

ISBN: 1118609808

Category: Technology & Engineering

Page: 736

View: 7431


Exhibiting both homogeneous and heterogeneous catalytic properties,nanocatalysts allow for rapid and selective chemicaltransformations, with the benefits of excellent product yield andease of catalyst separation and recovery. This book reviews thecatalytic performance and the synthesis and characterization ofnanocatalysts, examining the current state of the art and pointingthe way towards new avenues of research. Moreover, the authorsdiscuss new and emerging applications of nanocatalysts andnanocatalysis, from pharmaceuticals to fine chemicals to renewableenergy to biotransformations. Nanocatalysis features contributions from leadingresearch groups around the world. These contributions reflect athorough review of the current literature as well as theauthors’ first-hand experience designing and synthesizingnanocatalysts and developing new applications for them. Thebook’s nineteen chapters offer a broad perspective,covering: Nanocatalysis for carbon-carbon and carbon-heteroatom couplingreactions Nanocatalysis for various organic transformations in finechemical synthesis Nanocatalysis for oxidation, hydrogenation, and other relatedreactions Nanomaterial-based photocatalysis and biocatalysis Nanocatalysts to produce non-conventional energy such ashydrogen and biofuels Nanocatalysts and nano-biocatalysts in the chemicalindustry Readers will also learn about the latest spectroscopic andmicroscopy tools used in advanced characterization methods thatshed new light on nanocatalysts and nanocatalysis. Moreover, theauthors offer expert advice to help readers develop strategies toimprove catalytic performance. Summarizing and reviewing all the most important advances innanocatalysis over the last two decades, this book explains themany advantages of nanocatalysts over conventional homogeneous andheterogeneous catalysts, providing the information and guidanceneeded for designing green, sustainable catalytic processes.

The Way of Synthesis

Evolution of Design and Methods for Natural Products

Author: Tomas Hudlicky,Josephine W. Reed

Publisher: Wiley-VCH


Category: Science

Page: 1032

View: 2596


This two-colored textbook presents not only synthetic ways to design organic compounds, it also contains a compilation of the most important total synthesis of the last 50 years with a comparative view of multiple designs for the same targets. It explains different tactics and strategies, making it easy to apply to many problems, regardless of the synthetic question in hand. Following a historical view of the evolution of synthesis, the book goes on to look at principles and issues impacting synthesis and design as well as principles and issues of methods. The sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as Maytansine, Palytoxin, Brevetoxin B and Indinavir. The whole is rounded off with a look at future perspectives and, what makes this textbook extraordinairy, with personal recollections of the chemists, who synthesized these fascinating compounds. With its attractive layout highlighting key parts and tactics using a second color, this is a useful tool for organic chemists, lecturers and students in chemistry, as well as those working in the chemical industry. "I think, as will many organic chemists, that the Hudlicky book will be the Bible of synthetic organic chemistry, the past, the present and the future. A hallmark publication." (Victor Snieckus)